STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
dnaBReplicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (445 aa)    
Predicted Functional Partners:
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 
 0.960
dnaA
Replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
 
 
 
 0.921
KWZ75212.1
KEGG: iva:Isova_2736 4.7e-170 DNA polymerase III subunits gamma and tau; K02343 DNA polymerase III subunit gamma/tau; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.784
KWZ75030.1
KEGG: iva:Isova_0427 6.0e-115 DNA polymerase III, delta prime subunit; K02341 DNA polymerase III subunit delta'; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.723
KWZ74942.1
HRDC domain protein; KEGG: xce:Xcel_0786 8.9e-192 UvrD/REP helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.671
KWZ74957.1
MaoC-like protein; KEGG: cef:CE0913 0. fasA; fatty-acid synthase I K11533; Psort location: Cytoplasmic, score: 9.95.
     
 0.666
KWZ74677.1
KEGG: shn:Shewana3_3590 5.8e-14 single-strand binding protein K03111; Psort location: Cytoplasmic, score: 9.67.
 
 
 0.647
tuf
Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
   
 
 0.631
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.621
KWZ72552.1
KEGG: bfa:Bfae_10990 0. dnaE; DNA polymerase III subunit alpha; K02337 DNA polymerase III subunit alpha; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.602
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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