Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
trxAThioredoxin; Psort location: Cytoplasmic, score: 9.97; Belongs to the thioredoxin family. (106 aa)    
Predicted Functional Partners:
trxB
Thioredoxin-disulfide reductase; Psort location: Cytoplasmic, score: 9.97.
 
 0.998
groL
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.790
rho
Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
 
    0.756
KWZ74532.1
Hypothetical protein.
  
    0.694
KWZ74533.1
Hydrolase, NUDIX family; Psort location: Cytoplasmic, score: 7.50; Belongs to the Nudix hydrolase family.
       0.691
KWZ72982.1
Thioredoxin; KEGG: maf:MAF_13480 1.5e-22 thioredoxin K05838; Psort location: CytoplasmicMembrane, score: 9.55.
  
   
 0.683
KWZ75047.1
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 
 0.668
ahpC
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
 
 0.665
KWZ73861.1
Low molecular weight phosphotyrosine protein phosphatase; KEGG: kra:Krad_3711 1.0e-30 protein tyrosine phosphatase; K01104 protein-tyrosine phosphatase; Psort location: Cytoplasmic, score: 7.50; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
 
 0.647
KWZ74531.1
Putative integral membrane protein MviN; Psort location: CytoplasmicMembrane, score: 10.00.
       0.636
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.