STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
trxBThioredoxin-disulfide reductase; Psort location: Cytoplasmic, score: 9.97. (309 aa)    
Predicted Functional Partners:
trxA
Thioredoxin; Psort location: Cytoplasmic, score: 9.97; Belongs to the thioredoxin family.
 
 0.998
ahpC
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
 
 0.897
trxA-2
Thioredoxin; KEGG: cva:CVAR_2990 4.9e-33 trxA; thioredoxin; Psort location: Cytoplasmic, score: 9.97; Belongs to the thioredoxin family.
  
 
 0.888
KWZ72982.1
Thioredoxin; KEGG: maf:MAF_13480 1.5e-22 thioredoxin K05838; Psort location: CytoplasmicMembrane, score: 9.55.
  
 
 0.850
KWZ74532.1
Hypothetical protein.
       0.691
KWZ74533.1
Hydrolase, NUDIX family; Psort location: Cytoplasmic, score: 7.50; Belongs to the Nudix hydrolase family.
     
 0.691
KWZ74531.1
Putative integral membrane protein MviN; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.637
lpdA
Dihydrolipoyl dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.621
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.604
KWZ74785.1
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
     
 0.589
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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