Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
hemLGlutamate-1-semialdehyde-2,1-aminomutase; KEGG: pad:TIIST44_06205 5.2e-148 glutamate-1-semialdehyde 2,1-aminomutase; K01845 glutamate-1-semialdehyde 2,1-aminomutase; Psort location: Cytoplasmic, score: 9.67. (464 aa)    
Predicted Functional Partners:
KWZ74178.1
Porphobilinogen synthase; KEGG: pad:TIIST44_06210 2.9e-122 delta-aminolevulinic acid dehydratase; K01698 porphobilinogen synthase; Psort location: Cytoplasmic, score: 7.50; Belongs to the ALAD family.
 
 
 0.994
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.951
KWZ72689.1
Putative glutamate-1-semialdehyde-2,1-aminomutase; KEGG: pfr:PFREUD_19260 2.6e-178 hemL2; glutamate-1-semialdehyde 2,1-aminomutase K01845; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
  
 
0.922
hemA
glutamyl-tRNAGlu reductase domain protein; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 
 0.896
KWZ74183.1
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.679
KWZ74793.1
KEGG: mcu:HMPREF0573_10554 1.3e-55 gpmB; phosphoglycerate mutase; Psort location: Cytoplasmic, score: 7.50.
  
    0.661
KWZ74182.1
KEGG: cfl:Cfla_3436 1.1e-74 protoporphyrinogen oxidase K00231; Psort location: Cytoplasmic, score: 9.89.
 
  
 0.601
KWZ74957.1
MaoC-like protein; KEGG: cef:CE0913 0. fasA; fatty-acid synthase I K11533; Psort location: Cytoplasmic, score: 9.95.
     
 0.585
KWZ74180.1
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
  
 0.577
KWZ74174.1
PspC domain protein; Psort location: CytoplasmicMembrane, score: 9.55.
       0.576
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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