STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KWZ74179.1Hypothetical protein; KEGG: swi:Swit_1248 3.1e-15 methylated-DNA--protein-cysteine methyltransferase K00567; Psort location: Cytoplasmic, score: 7.50. (262 aa)    
Predicted Functional Partners:
KWZ72616.1
Putative methylated-DNA--[protein]-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
  
     0.768
KWZ74180.1
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
       0.689
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
       0.689
KWZ74182.1
KEGG: cfl:Cfla_3436 1.1e-74 protoporphyrinogen oxidase K00231; Psort location: Cytoplasmic, score: 9.89.
       0.689
KWZ74183.1
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
       0.653
KWZ74175.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; Psort location: CytoplasmicMembrane, score: 10.00.
 
    0.597
KWZ74178.1
Porphobilinogen synthase; KEGG: pad:TIIST44_06210 2.9e-122 delta-aminolevulinic acid dehydratase; K01698 porphobilinogen synthase; Psort location: Cytoplasmic, score: 7.50; Belongs to the ALAD family.
       0.549
KWZ74177.1
Methyltransferase domain protein; KEGG: aai:AARI_10310 4.2e-43 SAM-dependent methyltransferase; Psort location: Cytoplasmic, score: 7.50.
       0.532
KWZ74176.1
Transcriptional regulator, LuxR family; Psort location: Cytoplasmic, score: 9.97.
       0.501
KWZ74693.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
   0.444
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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