node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KWZ72689.1 | KWZ74178.1 | HMPREF3198_01716 | HMPREF3198_00735 | Putative glutamate-1-semialdehyde-2,1-aminomutase; KEGG: pfr:PFREUD_19260 2.6e-178 hemL2; glutamate-1-semialdehyde 2,1-aminomutase K01845; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Porphobilinogen synthase; KEGG: pad:TIIST44_06210 2.9e-122 delta-aminolevulinic acid dehydratase; K01698 porphobilinogen synthase; Psort location: Cytoplasmic, score: 7.50; Belongs to the ALAD family. | 0.976 |
KWZ72689.1 | KWZ74180.1 | HMPREF3198_01716 | HMPREF3198_00737 | Putative glutamate-1-semialdehyde-2,1-aminomutase; KEGG: pfr:PFREUD_19260 2.6e-178 hemL2; glutamate-1-semialdehyde 2,1-aminomutase K01845; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.457 |
KWZ72689.1 | KWZ74183.1 | HMPREF3198_01716 | HMPREF3198_00740 | Putative glutamate-1-semialdehyde-2,1-aminomutase; KEGG: pfr:PFREUD_19260 2.6e-178 hemL2; glutamate-1-semialdehyde 2,1-aminomutase K01845; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.478 |
KWZ72689.1 | hemA | HMPREF3198_01716 | HMPREF3198_00741 | Putative glutamate-1-semialdehyde-2,1-aminomutase; KEGG: pfr:PFREUD_19260 2.6e-178 hemL2; glutamate-1-semialdehyde 2,1-aminomutase K01845; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | glutamyl-tRNAGlu reductase domain protein; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.969 |
KWZ72689.1 | hemC | HMPREF3198_01716 | HMPREF3198_00738 | Putative glutamate-1-semialdehyde-2,1-aminomutase; KEGG: pfr:PFREUD_19260 2.6e-178 hemL2; glutamate-1-semialdehyde 2,1-aminomutase K01845; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.905 |
KWZ74178.1 | KWZ72689.1 | HMPREF3198_00735 | HMPREF3198_01716 | Porphobilinogen synthase; KEGG: pad:TIIST44_06210 2.9e-122 delta-aminolevulinic acid dehydratase; K01698 porphobilinogen synthase; Psort location: Cytoplasmic, score: 7.50; Belongs to the ALAD family. | Putative glutamate-1-semialdehyde-2,1-aminomutase; KEGG: pfr:PFREUD_19260 2.6e-178 hemL2; glutamate-1-semialdehyde 2,1-aminomutase K01845; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.976 |
KWZ74178.1 | KWZ74179.1 | HMPREF3198_00735 | HMPREF3198_00736 | Porphobilinogen synthase; KEGG: pad:TIIST44_06210 2.9e-122 delta-aminolevulinic acid dehydratase; K01698 porphobilinogen synthase; Psort location: Cytoplasmic, score: 7.50; Belongs to the ALAD family. | Hypothetical protein; KEGG: swi:Swit_1248 3.1e-15 methylated-DNA--protein-cysteine methyltransferase K00567; Psort location: Cytoplasmic, score: 7.50. | 0.549 |
KWZ74178.1 | KWZ74180.1 | HMPREF3198_00735 | HMPREF3198_00737 | Porphobilinogen synthase; KEGG: pad:TIIST44_06210 2.9e-122 delta-aminolevulinic acid dehydratase; K01698 porphobilinogen synthase; Psort location: Cytoplasmic, score: 7.50; Belongs to the ALAD family. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.959 |
KWZ74178.1 | KWZ74182.1 | HMPREF3198_00735 | HMPREF3198_00739 | Porphobilinogen synthase; KEGG: pad:TIIST44_06210 2.9e-122 delta-aminolevulinic acid dehydratase; K01698 porphobilinogen synthase; Psort location: Cytoplasmic, score: 7.50; Belongs to the ALAD family. | KEGG: cfl:Cfla_3436 1.1e-74 protoporphyrinogen oxidase K00231; Psort location: Cytoplasmic, score: 9.89. | 0.779 |
KWZ74178.1 | KWZ74183.1 | HMPREF3198_00735 | HMPREF3198_00740 | Porphobilinogen synthase; KEGG: pad:TIIST44_06210 2.9e-122 delta-aminolevulinic acid dehydratase; K01698 porphobilinogen synthase; Psort location: Cytoplasmic, score: 7.50; Belongs to the ALAD family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.874 |
KWZ74178.1 | hemA | HMPREF3198_00735 | HMPREF3198_00741 | Porphobilinogen synthase; KEGG: pad:TIIST44_06210 2.9e-122 delta-aminolevulinic acid dehydratase; K01698 porphobilinogen synthase; Psort location: Cytoplasmic, score: 7.50; Belongs to the ALAD family. | glutamyl-tRNAGlu reductase domain protein; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.970 |
KWZ74178.1 | hemC | HMPREF3198_00735 | HMPREF3198_00738 | Porphobilinogen synthase; KEGG: pad:TIIST44_06210 2.9e-122 delta-aminolevulinic acid dehydratase; K01698 porphobilinogen synthase; Psort location: Cytoplasmic, score: 7.50; Belongs to the ALAD family. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
KWZ74178.1 | hemH | HMPREF3198_00735 | HMPREF3198_00742 | Porphobilinogen synthase; KEGG: pad:TIIST44_06210 2.9e-122 delta-aminolevulinic acid dehydratase; K01698 porphobilinogen synthase; Psort location: Cytoplasmic, score: 7.50; Belongs to the ALAD family. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.629 |
KWZ74178.1 | hemL | HMPREF3198_00735 | HMPREF3198_00730 | Porphobilinogen synthase; KEGG: pad:TIIST44_06210 2.9e-122 delta-aminolevulinic acid dehydratase; K01698 porphobilinogen synthase; Psort location: Cytoplasmic, score: 7.50; Belongs to the ALAD family. | Glutamate-1-semialdehyde-2,1-aminomutase; KEGG: pad:TIIST44_06205 5.2e-148 glutamate-1-semialdehyde 2,1-aminomutase; K01845 glutamate-1-semialdehyde 2,1-aminomutase; Psort location: Cytoplasmic, score: 9.67. | 0.995 |
KWZ74179.1 | KWZ74178.1 | HMPREF3198_00736 | HMPREF3198_00735 | Hypothetical protein; KEGG: swi:Swit_1248 3.1e-15 methylated-DNA--protein-cysteine methyltransferase K00567; Psort location: Cytoplasmic, score: 7.50. | Porphobilinogen synthase; KEGG: pad:TIIST44_06210 2.9e-122 delta-aminolevulinic acid dehydratase; K01698 porphobilinogen synthase; Psort location: Cytoplasmic, score: 7.50; Belongs to the ALAD family. | 0.549 |
KWZ74179.1 | KWZ74180.1 | HMPREF3198_00736 | HMPREF3198_00737 | Hypothetical protein; KEGG: swi:Swit_1248 3.1e-15 methylated-DNA--protein-cysteine methyltransferase K00567; Psort location: Cytoplasmic, score: 7.50. | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.689 |
KWZ74179.1 | KWZ74182.1 | HMPREF3198_00736 | HMPREF3198_00739 | Hypothetical protein; KEGG: swi:Swit_1248 3.1e-15 methylated-DNA--protein-cysteine methyltransferase K00567; Psort location: Cytoplasmic, score: 7.50. | KEGG: cfl:Cfla_3436 1.1e-74 protoporphyrinogen oxidase K00231; Psort location: Cytoplasmic, score: 9.89. | 0.689 |
KWZ74179.1 | KWZ74183.1 | HMPREF3198_00736 | HMPREF3198_00740 | Hypothetical protein; KEGG: swi:Swit_1248 3.1e-15 methylated-DNA--protein-cysteine methyltransferase K00567; Psort location: Cytoplasmic, score: 7.50. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.654 |
KWZ74179.1 | hemC | HMPREF3198_00736 | HMPREF3198_00738 | Hypothetical protein; KEGG: swi:Swit_1248 3.1e-15 methylated-DNA--protein-cysteine methyltransferase K00567; Psort location: Cytoplasmic, score: 7.50. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.689 |
KWZ74180.1 | KWZ72689.1 | HMPREF3198_00737 | HMPREF3198_01716 | uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Putative glutamate-1-semialdehyde-2,1-aminomutase; KEGG: pfr:PFREUD_19260 2.6e-178 hemL2; glutamate-1-semialdehyde 2,1-aminomutase K01845; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.457 |