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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (353 aa)    
Predicted Functional Partners:
KWZ74186.1
Chlorite O(2)-lyase; KEGG: pcn:TIB1ST10_01590 8.4e-61 ferrochelatase, HemH; K01772 ferrochelatase; Psort location: Cytoplasmic, score: 7.50.
 
 0.998
KWZ74182.1
KEGG: cfl:Cfla_3436 1.1e-74 protoporphyrinogen oxidase K00231; Psort location: Cytoplasmic, score: 9.89.
 
 
 0.997
KWZ74183.1
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.983
KWZ72877.1
Hypothetical protein; KEGG: tra:Trad_1785 3.3e-27 NAD(P)H dehydrogenase (quinone); K00230 menaquinone-dependent protoporphyrinogen oxidase; Psort location: CytoplasmicMembrane, score: 9.55.
    
 0.929
hemA
glutamyl-tRNAGlu reductase domain protein; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.889
KWZ74746.1
Radical SAM domain protein; KEGG: cti:RALTA_B0668 7.1e-09 pqqE1; pyrroloquinoline quinone biosynthesis protein pqqe K06139; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.883
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
  
 0.868
KWZ73887.1
Periplasmic binding protein; KEGG: ttn:TTX_0257 0.0063 fepB1; Fe3+-hydroxamate ABC transporter periplasmic protein.
  
  
 0.751
KWZ74180.1
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
  
 0.658
KWZ74178.1
Porphobilinogen synthase; KEGG: pad:TIIST44_06210 2.9e-122 delta-aminolevulinic acid dehydratase; K01698 porphobilinogen synthase; Psort location: Cytoplasmic, score: 7.50; Belongs to the ALAD family.
  
  
 0.629
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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