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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KWZ74220.1Type I restriction enzyme HsdR protein; KEGG: fps:FP1567 7.9e-129 endonuclease-methyltransferase fusion protein; Psort location: Cytoplasmic, score: 7.50. (985 aa)    
Predicted Functional Partners:
KWZ74221.1
Putative modification methylase Eco57IB; KEGG: fps:FP1566 4.1e-68 modification methyltransferase.
 
   
 0.946
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
   0.707
KWZ74222.1
Hypothetical protein; KEGG: ral:Rumal_2514 1.1e-10 XRE family transcriptional regulator K00558.
       0.630
KWZ74223.1
Hypothetical protein; KEGG: bce:BC1852 0.0017 exonuclease SbcC K03546; Psort location: Cytoplasmic, score: 7.50.
       0.630
KWZ72197.1
Hypothetical protein; KEGG: mma:MM_0156 1.0e-149 type IIS restriction enzyme K01155; Psort location: CytoplasmicMembrane, score: 9.55.
 
    0.606
KWZ74225.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
       0.597
KWZ74224.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
       0.584
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
   0.558
brxC
Hypothetical protein; KEGG: isc:IscW_ISCW022794 0.0011 hyaluronan mediated motility receptor, putative.
 
    0.545
KWZ72199.1
TIGR02688 family protein; KEGG: dvg:Deval_1299 2.9e-186 hypothetical protein; K01338 ATP-dependent Lon protease; Psort location: Cytoplasmic, score: 7.50.
 
    0.512
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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