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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purAAdenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (427 aa)    
Predicted Functional Partners:
KWZ74538.1
Putative adenylosuccinate lyase; Psort location: Cytoplasmic, score: 7.50.
 0.999
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.995
purH
Putative phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; KEGG: mcu:HMPREF0573_10110 7.1e-199 purH; IMP cyclohydrolase K00602; Psort location: Cytoplasmic, score: 7.50.
  
 0.990
hpt
KEGG: tbi:Tbis_3448 1.3e-66 hypoxanthine phosphoribosyltransferase K00760; Psort location: Cytoplasmic, score: 9.97; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
 0.967
argG
KEGG: cfi:Celf_1667 1.0e-181 argininosuccinate synthase K01940; Psort location: Cytoplasmic, score: 7.50; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 
 0.936
pyrB
KEGG: mcu:HMPREF0573_11715 2.1e-121 pyrB; aspartate carbamoyltransferase K00609; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
 
 0.936
KWZ74889.1
Hypothetical protein; KEGG: bfa:Bfae_21010 1.3e-66 asparagine synthase (glutamine-hydrolyzing); K01953 asparagine synthase (glutamine-hydrolysing); Psort location: Cytoplasmic, score: 7.50.
   
 
 0.930
KWZ75209.1
Aspartate kinase II; KEGG: mcu:HMPREF0573_10651 5.1e-157 ask; aspartate kinase K00928; Psort location: Cytoplasmic, score: 7.50; Belongs to the aspartokinase family.
  
 
  0.924
KWZ74836.1
Putative aspartate transaminase; KEGG: mcu:HMPREF0573_11145 2.9e-154 aspC; aspartate transaminase.
   
 0.920
aspA-2
Aspartate ammonia-lyase; KEGG: pfr:PFREUD_16330 1.3e-181 aspA2; aspartate ammonia-lyase K01744; Psort location: Cytoplasmic, score: 9.97.
     
 0.913
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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