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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KWZ74337.1Putative 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (787 aa)    
Predicted Functional Partners:
KWZ74770.1
O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; KEGG: jde:Jden_2111 2.0e-146 O-acetylhomoserine/O-acetylserine sulfhydrylase K01740; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.968
KWZ75051.1
S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
    
 0.959
KWZ74336.1
KEGG: ske:Sked_00590 1.9e-54 5,10-methylenetetrahydrofolate reductase; K00297 methylenetetrahydrofolate reductase (NADPH); Psort location: Cytoplasmic, score: 7.50.
 
 0.959
cysK
KEGG: cfl:Cfla_1390 2.4e-104 cysteine synthase; K01738 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
     
 0.936
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
   
 
 0.935
KWZ74251.1
KEGG: crd:CRES_0890 1.4e-195 metK2; S-adenosylmethionine synthetase K00789; Psort location: Cytoplasmic, score: 9.97; Belongs to the AdoMet synthase family.
  
 0.923
KWZ74434.1
KEGG: mcu:HMPREF0573_11248 6.3e-191 S-adenosylmethionine synthetase K00789; Psort location: Cytoplasmic, score: 9.97; Belongs to the AdoMet synthase family.
  
 0.923
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 0.923
KWZ72397.1
Aminotransferase, class I/II; KEGG: mcu:HMPREF0573_10336 3.0e-72 putative cystathionine beta-lyase; K14155 cystathione beta-lyase; Psort location: Cytoplasmic, score: 7.50.
    
  0.912
KWZ72448.1
KEGG: bfa:Bfae_08030 2.4e-86 cystathionine beta-lyase/cystathionine gamma-synthase; K01760 cystathionine beta-lyase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.881
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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