STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KWZ74337.1Putative 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (787 aa)    
Predicted Functional Partners:
KWZ74336.1
KEGG: ske:Sked_00590 1.9e-54 5,10-methylenetetrahydrofolate reductase; K00297 methylenetetrahydrofolate reductase (NADPH); Psort location: Cytoplasmic, score: 7.50.
 
  
 0.941
KWZ72290.1
KEGG: bld:BLi01290 4.8e-113 yjcJ; cystathionine beta-lyase; K01760 cystathionine beta-lyase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.941
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 0.941
KWZ74770.1
O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; KEGG: jde:Jden_2111 2.0e-146 O-acetylhomoserine/O-acetylserine sulfhydrylase K01740; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.924
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
     
 0.906
KWZ73008.1
Homoserine dehydrogenase; KEGG: mcu:HMPREF0573_10380 3.3e-75 hom; homoserine dehydrogenase K00003.
   
 
 0.849
cysK
KEGG: cfl:Cfla_1390 2.4e-104 cysteine synthase; K01738 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
   
 
 0.833
KWZ74251.1
KEGG: crd:CRES_0890 1.4e-195 metK2; S-adenosylmethionine synthetase K00789; Psort location: Cytoplasmic, score: 9.97; Belongs to the AdoMet synthase family.
  
 0.708
KWZ74434.1
KEGG: mcu:HMPREF0573_11248 6.3e-191 S-adenosylmethionine synthetase K00789; Psort location: Cytoplasmic, score: 9.97; Belongs to the AdoMet synthase family.
  
 0.708
KWZ75051.1
S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
    
 0.575
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.