STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KWZ74442.1Endopeptidase Clp; KEGG: mcu:HMPREF0573_11238 7.7e-99 ATP-dependent Clp protease proteolytic subunit ClpP; K01358 ATP-dependent Clp protease, protease subunit; Psort location: Cytoplasmic, score: 7.50; Belongs to the peptidase S14 family. (287 aa)    
Predicted Functional Partners:
clpP-2
Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
 
 
 0.974
KWZ74441.1
Phage portal protein, HK97 family.
    0.951
clpX
ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
  
 0.933
KWZ74443.1
Phage major capsid protein, HK97 family.
 
    0.911
clpB
ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
   
 
 0.859
KWZ74745.1
Negative regulator of genetic competence ClpC/MecB; KEGG: mbb:BCG_3661c 0. clpC; putative ATP-dependent Clp protease ATP-binding subunit ClpC K03696; Psort location: Cytoplasmic, score: 9.97.
   
 
 0.859
KWZ74261.1
Phage portal protein, HK97 family; Psort location: Cytoplasmic, score: 7.50.
    0.791
KWZ74934.1
ATP-dependent Clp protease adaptor protein ClpS; Psort location: CytoplasmicMembrane, score: 9.55; Belongs to the ClpS family.
   
 
 0.714
groS
Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
  
 
 0.703
KWZ74263.1
Phage major capsid protein, HK97 family.
 
    0.666
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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