STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KWZ74442.1Endopeptidase Clp; KEGG: mcu:HMPREF0573_11238 7.7e-99 ATP-dependent Clp protease proteolytic subunit ClpP; K01358 ATP-dependent Clp protease, protease subunit; Psort location: Cytoplasmic, score: 7.50; Belongs to the peptidase S14 family. (287 aa)    
Predicted Functional Partners:
KWZ74441.1
Phage portal protein, HK97 family.
    0.950
clpP-2
Endopeptidase Clp; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
 
 
 0.936
clpX
ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
  
 0.912
KWZ74443.1
Phage major capsid protein, HK97 family.
 
    0.909
KWZ74261.1
Phage portal protein, HK97 family; Psort location: Cytoplasmic, score: 7.50.
    0.788
clpB
ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
   
 
 0.764
KWZ74745.1
Negative regulator of genetic competence ClpC/MecB; KEGG: mbb:BCG_3661c 0. clpC; putative ATP-dependent Clp protease ATP-binding subunit ClpC K03696; Psort location: Cytoplasmic, score: 9.97.
   
 
 0.764
KWZ74263.1
Phage major capsid protein, HK97 family.
 
    0.661
KWZ74445.1
Putative phage head-tail adaptor; Psort location: Cytoplasmic, score: 7.50.
  
    0.650
KWZ74446.1
Phage protein, HK97 gp10 family; Psort location: CytoplasmicMembrane, score: 9.55.
  
    0.648
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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