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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ilvDDihydroxy-acid dehydratase; KEGG: mcu:HMPREF0573_11178 3.6e-243 ilvD; dihydroxy-acid dehydratase K01687; Psort location: Cytoplasmic, score: 7.50; Belongs to the IlvD/Edd family. (600 aa)    
Predicted Functional Partners:
KWZ73910.1
Branched-chain-amino-acid transaminase; KEGG: mcu:HMPREF0573_11483 4.8e-113 ilvE; branched-subunit-amino-acid transaminase K00826; Psort location: Cytoplasmic, score: 7.50.
  
 0.997
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 
 0.986
KWZ73912.1
2-isopropylmalate synthase/homocitrate synthase family protein; KEGG: ske:Sked_10800 4.7e-147 2-isopropylmalate synthase; K01649 2-isopropylmalate synthase; Psort location: Cytoplasmic, score: 7.50; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 
 0.985
KWZ73909.1
KEGG: bcv:Bcav_1417 6.9e-114 3-isopropylmalate dehydrogenase K00052; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.940
KWZ75620.1
Hypothetical protein; KEGG: smz:SMD_1225 2.2e-14 Aminodeoxychorismate lyase; Psort location: Cytoplasmic, score: 7.50.
  
 0.890
leuC
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
  
 0.888
KWZ75240.1
Thiamine pyrophosphate enzyme, TPP binding domain protein; KEGG: mlu:Mlut_02710 1.3e-192 pyruvate dehydrogenase (cytochrome) K00156; Psort location: CytoplasmicMembrane, score: 9.51; Belongs to the TPP enzyme family.
 
 0.887
KWZ75564.1
Phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
   
 0.882
KWZ73167.1
Shikimate kinase; KEGG: cfl:Cfla_0786 2.0e-45 thermoresistant glucokinase family carbohydrate kinase K00851; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.877
pgl
6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
  
 
 0.876
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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