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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (212 aa)    
Predicted Functional Partners:
pyrH
UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
 
 0.979
pyrF
KEGG: iva:Isova_1604 2.0e-68 Orotidine 5'-phosphate decarboxylase K01591; Psort location: Cytoplasmic, score: 7.50; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
 
 0.976
tadA
Cytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
   
 0.955
pyrR
Pyrimidine operon regulatory protein/uracil phosphoribosyltransferase PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
     
 0.952
deoD
KEGG: ckp:ckrop_0402 6.7e-84 deoD; purine nucleoside phosphorylase K03784; Psort location: Cytoplasmic, score: 9.67.
    
  0.916
KWZ75064.1
Hypothetical protein; KEGG: aai:AARI_25430 2.0e-19 aminodeoxychorismate synthase K13950; Psort location: CytoplasmicMembrane, score: 8.16.
  
 0.915
KWZ73012.1
KEGG: mcu:HMPREF0573_11182 3.0e-49 ribose-5-phosphate isomerase B K01808; Psort location: Cytoplasmic, score: 7.50.
 
    0.912
KWZ72166.1
Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
   
 
 0.909
KWZ72405.1
Ribose 5-phosphate isomerase; KEGG: paz:TIA2EST2_11315 3.2e-52 putative ribose 5-phosphate isomerase; K01808 ribose 5-phosphate isomerase B; Psort location: Cytoplasmic, score: 7.50.
 
    0.871
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
  
  
 0.860
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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