node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KWZ73872.1 | KWZ73873.1 | HMPREF3198_01177 | HMPREF3198_01178 | KEGG: cga:Celgi_2368 1.9e-40 glutamine amidotransferase; K01951 GMP synthase (glutamine-hydrolysing); Psort location: Cytoplasmic, score: 7.50. | Carboxylate-amine ligase, YbdK family; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. | 0.729 |
KWZ73872.1 | apt | HMPREF3198_01177 | HMPREF3198_02169 | KEGG: cga:Celgi_2368 1.9e-40 glutamine amidotransferase; K01951 GMP synthase (glutamine-hydrolysing); Psort location: Cytoplasmic, score: 7.50. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.936 |
KWZ73872.1 | gmk | HMPREF3198_01177 | HMPREF3198_02203 | KEGG: cga:Celgi_2368 1.9e-40 glutamine amidotransferase; K01951 GMP synthase (glutamine-hydrolysing); Psort location: Cytoplasmic, score: 7.50. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.921 |
KWZ73872.1 | guaA | HMPREF3198_01177 | HMPREF3198_01611 | KEGG: cga:Celgi_2368 1.9e-40 glutamine amidotransferase; K01951 GMP synthase (glutamine-hydrolysing); Psort location: Cytoplasmic, score: 7.50. | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | 0.942 |
KWZ73872.1 | guaB | HMPREF3198_01177 | HMPREF3198_01487 | KEGG: cga:Celgi_2368 1.9e-40 glutamine amidotransferase; K01951 GMP synthase (glutamine-hydrolysing); Psort location: Cytoplasmic, score: 7.50. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.985 |
KWZ73872.1 | hpt | HMPREF3198_01177 | HMPREF3198_00414 | KEGG: cga:Celgi_2368 1.9e-40 glutamine amidotransferase; K01951 GMP synthase (glutamine-hydrolysing); Psort location: Cytoplasmic, score: 7.50. | KEGG: tbi:Tbis_3448 1.3e-66 hypoxanthine phosphoribosyltransferase K00760; Psort location: Cytoplasmic, score: 9.97; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.922 |
KWZ73872.1 | nadE | HMPREF3198_01177 | HMPREF3198_01623 | KEGG: cga:Celgi_2368 1.9e-40 glutamine amidotransferase; K01951 GMP synthase (glutamine-hydrolysing); Psort location: Cytoplasmic, score: 7.50. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.511 |
KWZ73872.1 | pheT | HMPREF3198_01177 | HMPREF3198_01230 | KEGG: cga:Celgi_2368 1.9e-40 glutamine amidotransferase; K01951 GMP synthase (glutamine-hydrolysing); Psort location: Cytoplasmic, score: 7.50. | phenylalanine--tRNA ligase, beta subunit; KEGG: mcu:HMPREF0573_10030 5.7e-245 pheT; phenylalanine--tRNA ligase K01890; Psort location: Cytoplasmic, score: 9.97; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.717 |
KWZ73872.1 | rdgB | HMPREF3198_01177 | HMPREF3198_00583 | KEGG: cga:Celgi_2368 1.9e-40 glutamine amidotransferase; K01951 GMP synthase (glutamine-hydrolysing); Psort location: Cytoplasmic, score: 7.50. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.915 |
KWZ73872.1 | rplK | HMPREF3198_01177 | HMPREF3198_00480 | KEGG: cga:Celgi_2368 1.9e-40 glutamine amidotransferase; K01951 GMP synthase (glutamine-hydrolysing); Psort location: Cytoplasmic, score: 7.50. | Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.573 |
KWZ73873.1 | KWZ73872.1 | HMPREF3198_01178 | HMPREF3198_01177 | Carboxylate-amine ligase, YbdK family; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. | KEGG: cga:Celgi_2368 1.9e-40 glutamine amidotransferase; K01951 GMP synthase (glutamine-hydrolysing); Psort location: Cytoplasmic, score: 7.50. | 0.729 |
apt | KWZ73872.1 | HMPREF3198_02169 | HMPREF3198_01177 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | KEGG: cga:Celgi_2368 1.9e-40 glutamine amidotransferase; K01951 GMP synthase (glutamine-hydrolysing); Psort location: Cytoplasmic, score: 7.50. | 0.936 |
apt | gmk | HMPREF3198_02169 | HMPREF3198_02203 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.969 |
apt | guaA | HMPREF3198_02169 | HMPREF3198_01611 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP. | 0.991 |
apt | guaB | HMPREF3198_02169 | HMPREF3198_01487 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.930 |
apt | hpt | HMPREF3198_02169 | HMPREF3198_00414 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | KEGG: tbi:Tbis_3448 1.3e-66 hypoxanthine phosphoribosyltransferase K00760; Psort location: Cytoplasmic, score: 9.97; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.972 |
apt | nadE | HMPREF3198_02169 | HMPREF3198_01623 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.432 |
apt | pheT | HMPREF3198_02169 | HMPREF3198_01230 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | phenylalanine--tRNA ligase, beta subunit; KEGG: mcu:HMPREF0573_10030 5.7e-245 pheT; phenylalanine--tRNA ligase K01890; Psort location: Cytoplasmic, score: 9.97; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.445 |
apt | rdgB | HMPREF3198_02169 | HMPREF3198_00583 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.554 |
gmk | KWZ73872.1 | HMPREF3198_02203 | HMPREF3198_01177 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | KEGG: cga:Celgi_2368 1.9e-40 glutamine amidotransferase; K01951 GMP synthase (glutamine-hydrolysing); Psort location: Cytoplasmic, score: 7.50. | 0.921 |