KWZ72914.1 protein (Winkia neuii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

KWZ72914.1

Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (219 aa)

Predicted Functional Partners:

lepB

0.929

KWZ74693.1

0.922

KWZ74942.1

0.857

KWZ72913.1

0.773

rnhA

0.752

KWZ74326.1

0.752

dnaG

0.739

KWZ74816.1

0.738

polA

0.735

KWZ74814.1

0.725

Your Current Organism:

Winkia neuii

NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KWZ72913.1	KWZ72914.1	HMPREF3198_01267	HMPREF3198_01268	Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.773
KWZ72913.1	dnaG	HMPREF3198_01267	HMPREF3198_01270	Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.	DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.	0.532
KWZ72913.1	lepB	HMPREF3198_01267	HMPREF3198_01269	Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.	KEGG: jde:Jden_0990 1.0e-46 signal peptidase I; K03100 signal peptidase I; Psort location: CytoplasmicMembrane, score: 9.51; Belongs to the peptidase S26 family.	0.773
KWZ72914.1	KWZ72913.1	HMPREF3198_01268	HMPREF3198_01267	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.	0.773
KWZ72914.1	KWZ74326.1	HMPREF3198_01268	HMPREF3198_00884	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	Hypothetical protein; KEGG: xce:Xcel_0160 2.4e-09 ribonuclease H; K03469 ribonuclease HI; Psort location: Cytoplasmic, score: 7.50.	0.752
KWZ72914.1	KWZ74693.1	HMPREF3198_01268	HMPREF3198_00688	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	0.922
KWZ72914.1	KWZ74814.1	HMPREF3198_01268	HMPREF3198_00451	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	NADH-quinone oxidoreductase, E subunit; KEGG: mcu:HMPREF0573_10996 2.7e-80 nuoE; NADH dehydrogenase K00334; Psort location: Cytoplasmic, score: 9.97.	0.725
KWZ72914.1	KWZ74816.1	HMPREF3198_01268	HMPREF3198_00453	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	KEGG: ahe:Arch_0299 3.0e-239 NADH-quinone oxidoreductase subunit G; K00336 NADH-quinone oxidoreductase subunit G; Psort location: Cytoplasmic, score: 9.97.	0.738
KWZ72914.1	KWZ74942.1	HMPREF3198_01268	HMPREF3198_00586	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	HRDC domain protein; KEGG: xce:Xcel_0786 8.9e-192 UvrD/REP helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97.	0.857
KWZ72914.1	dnaG	HMPREF3198_01268	HMPREF3198_01270	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.	0.739
KWZ72914.1	lepB	HMPREF3198_01268	HMPREF3198_01269	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	KEGG: jde:Jden_0990 1.0e-46 signal peptidase I; K03100 signal peptidase I; Psort location: CytoplasmicMembrane, score: 9.51; Belongs to the peptidase S26 family.	0.929
KWZ72914.1	polA	HMPREF3198_01268	HMPREF3198_02272	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.735
KWZ72914.1	rnhA	HMPREF3198_01268	HMPREF3198_00351	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.752
KWZ74326.1	KWZ72914.1	HMPREF3198_00884	HMPREF3198_01268	Hypothetical protein; KEGG: xce:Xcel_0160 2.4e-09 ribonuclease H; K03469 ribonuclease HI; Psort location: Cytoplasmic, score: 7.50.	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.752
KWZ74326.1	KWZ74942.1	HMPREF3198_00884	HMPREF3198_00586	Hypothetical protein; KEGG: xce:Xcel_0160 2.4e-09 ribonuclease H; K03469 ribonuclease HI; Psort location: Cytoplasmic, score: 7.50.	HRDC domain protein; KEGG: xce:Xcel_0786 8.9e-192 UvrD/REP helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97.	0.555
KWZ74326.1	polA	HMPREF3198_00884	HMPREF3198_02272	Hypothetical protein; KEGG: xce:Xcel_0160 2.4e-09 ribonuclease H; K03469 ribonuclease HI; Psort location: Cytoplasmic, score: 7.50.	DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.861
KWZ74693.1	KWZ72914.1	HMPREF3198_00688	HMPREF3198_01268	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.	0.922
KWZ74693.1	KWZ74942.1	HMPREF3198_00688	HMPREF3198_00586	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	HRDC domain protein; KEGG: xce:Xcel_0786 8.9e-192 UvrD/REP helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97.	0.999
KWZ74693.1	dnaG	HMPREF3198_00688	HMPREF3198_01270	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.	0.654
KWZ74693.1	polA	HMPREF3198_00688	HMPREF3198_02272	DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]	DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.999