STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lepBKEGG: jde:Jden_0990 1.0e-46 signal peptidase I; K03100 signal peptidase I; Psort location: CytoplasmicMembrane, score: 9.51; Belongs to the peptidase S26 family. (230 aa)    
Predicted Functional Partners:
KWZ72914.1
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
    0.930
KWZ72913.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
       0.763
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
  
 
 0.735
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
  
 0.700
KWZ72910.1
KEGG: apb:SAR116_0616 7.2e-32 DNA protecting protein DprA K04096; Psort location: Cytoplasmic, score: 7.50.
 
     0.679
xerC
Phage integrase, SAM-like domain protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
     
 0.629
KWZ72912.1
Hypothetical protein; KEGG: sen:SACE_6045 2.4e-15 endonuclease K07460; Psort location: Cytoplasmic, score: 7.50; Belongs to the UPF0102 family.
  
    0.621
KWZ72911.1
Mg chelatase-like protein; KEGG: bde:BDP_0806 1.7e-103 ATPase-like magnesium chelatase subunit ChlI K07391; Psort location: Cytoplasmic, score: 7.50.
       0.608
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
  
  
 0.608
KWZ74700.1
Membrane protein insertase, YidC/Oxa1 family; KEGG: ptm:GSPATT00006636001 0.00047 hypothetical protein; K12735 peptidyl-prolyl cis-trans isomerase-like 4; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.605
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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