| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KWZ73001.1 | prfA | HMPREF3198_01358 | HMPREF3198_01359 | KEGG: ahe:Arch_0357 3.5e-55 protein-(glutamine-N5) methyltransferase; K02493 release factor glutamine methyltransferase; Belongs to the protein N5-glutamine methyltransferase family. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.992 |
| KWZ73001.1 | rpmE | HMPREF3198_01358 | HMPREF3198_01360 | KEGG: ahe:Arch_0357 3.5e-55 protein-(glutamine-N5) methyltransferase; K02493 release factor glutamine methyltransferase; Belongs to the protein N5-glutamine methyltransferase family. | Ribosomal protein L31; Binds the 23S rRNA. | 0.681 |
| KWZ75035.1 | prfA | HMPREF3198_00333 | HMPREF3198_01359 | Methyltransferase, HemK family; KEGG: cro:ROD_18011 4.6e-15 hemK; protein methyltransferase hemk (protein-glutamine N methyltransferase) K02493; Psort location: CytoplasmicMembrane, score: 8.16; Belongs to the methyltransferase superfamily. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.927 |
| prfA | KWZ73001.1 | HMPREF3198_01359 | HMPREF3198_01358 | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | KEGG: ahe:Arch_0357 3.5e-55 protein-(glutamine-N5) methyltransferase; K02493 release factor glutamine methyltransferase; Belongs to the protein N5-glutamine methyltransferase family. | 0.992 |
| prfA | KWZ75035.1 | HMPREF3198_01359 | HMPREF3198_00333 | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | Methyltransferase, HemK family; KEGG: cro:ROD_18011 4.6e-15 hemK; protein methyltransferase hemk (protein-glutamine N methyltransferase) K02493; Psort location: CytoplasmicMembrane, score: 8.16; Belongs to the methyltransferase superfamily. | 0.927 |
| prfA | rplC | HMPREF3198_01359 | HMPREF3198_01581 | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.931 |
| prfA | rplM | HMPREF3198_01359 | HMPREF3198_01504 | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.957 |
| prfA | rplO | HMPREF3198_01359 | HMPREF3198_01558 | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.914 |
| prfA | rplS | HMPREF3198_01359 | HMPREF3198_01835 | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.917 |
| prfA | rplT | HMPREF3198_01359 | HMPREF3198_01924 | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.933 |
| prfA | rpmE | HMPREF3198_01359 | HMPREF3198_01360 | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | Ribosomal protein L31; Binds the 23S rRNA. | 0.957 |
| prfA | rpsI | HMPREF3198_01359 | HMPREF3198_01503 | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | Ribosomal protein S9; KEGG: apb:SAR116_0492 4.8e-26 30S ribosomal protein S9 K02996; Psort location: Cytoplasmic, score: 9.67; Belongs to the universal ribosomal protein uS9 family. | 0.945 |
| prfA | rpsP | HMPREF3198_01359 | HMPREF3198_01830 | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | Ribosomal protein S16; KEGG: apb:SAR116_1817 2.7e-23 30S ribosomal protein S16 K02959; Psort location: Cytoplasmic, score: 9.67; Belongs to the bacterial ribosomal protein bS16 family. | 0.919 |
| rplC | prfA | HMPREF3198_01581 | HMPREF3198_01359 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.931 |
| rplC | rplM | HMPREF3198_01581 | HMPREF3198_01504 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.998 |
| rplC | rplO | HMPREF3198_01581 | HMPREF3198_01558 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.999 |
| rplC | rplS | HMPREF3198_01581 | HMPREF3198_01835 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.996 |
| rplC | rplT | HMPREF3198_01581 | HMPREF3198_01924 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.997 |
| rplC | rpmE | HMPREF3198_01581 | HMPREF3198_01360 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | Ribosomal protein L31; Binds the 23S rRNA. | 0.953 |
| rplC | rpsI | HMPREF3198_01581 | HMPREF3198_01503 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | Ribosomal protein S9; KEGG: apb:SAR116_0492 4.8e-26 30S ribosomal protein S9 K02996; Psort location: Cytoplasmic, score: 9.67; Belongs to the universal ribosomal protein uS9 family. | 0.998 |