STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KWZ73008.1Homoserine dehydrogenase; KEGG: mcu:HMPREF0573_10380 3.3e-75 hom; homoserine dehydrogenase K00003. (272 aa)    
Predicted Functional Partners:
KWZ73007.1
ACT domain protein; KEGG: ske:Sked_09870 6.6e-29 homoserine dehydrogenase; K00003 homoserine dehydrogenase; Psort location: Cytoplasmic, score: 7.50.
     0.994
metXA
Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
 
 
 0.980
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
 
 
 0.978
KWZ75209.1
Aspartate kinase II; KEGG: mcu:HMPREF0573_10651 5.1e-157 ask; aspartate kinase K00928; Psort location: Cytoplasmic, score: 7.50; Belongs to the aspartokinase family.
 
 0.956
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
  
 0.937
KWZ74355.1
Dihydrodipicolinate synthetase family protein; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. Belongs to the DapA family.
    
 0.907
KWZ72458.1
Threonine synthase; KEGG: cpk:Cp1002_1475 1.9e-150 thrC; Threonine synthase; K01733 threonine synthase; Psort location: Cytoplasmic, score: 7.50.
 
 
 0.903
KWZ74770.1
O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; KEGG: jde:Jden_2111 2.0e-146 O-acetylhomoserine/O-acetylserine sulfhydrylase K01740; Psort location: Cytoplasmic, score: 9.97.
 
 
 0.865
KWZ72290.1
KEGG: bld:BLi01290 4.8e-113 yjcJ; cystathionine beta-lyase; K01760 cystathionine beta-lyase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.855
KWZ74337.1
Putative 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
   
 
 0.849
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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