Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
gene fusions
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sbcDExonuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (379 aa)    
Predicted Functional Partners:
KWZ73027.1
Putative DNA sulfur modification protein DndD; KEGG: cnc:CNE_2c01810 3.9e-88 sbcC; DNA repair exonuclease SbcC K03546; Psort location: Cytoplasmic, score: 9.97.
 
 0.996
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 0.953
KWZ74942.1
HRDC domain protein; KEGG: xce:Xcel_0786 8.9e-192 UvrD/REP helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97.
  
 0.946
KWZ74223.1
Hypothetical protein; KEGG: bce:BC1852 0.0017 exonuclease SbcC K03546; Psort location: Cytoplasmic, score: 7.50.
  
 0.909
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.723
KWZ72524.1
Hypothetical protein; KEGG: bcv:Bcav_2435 3.8e-136 helicase c2; K03722 ATP-dependent DNA helicase DinG; Psort location: Cytoplasmic, score: 7.50.
   
 0.668
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
       0.647
rsgA
Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
       0.643
KWZ72767.1
Protein, SNF2 family; KEGG: mph:MLP_35040 1.9e-132 putative helicase; Psort location: CytoplasmicMembrane, score: 8.16.
 
   0.614
KWZ75256.1
Hypothetical protein; KEGG: ase:ACPL_5539 5.2e-37 Regulator of nonsense transcripts 1; Psort location: Cytoplasmic, score: 7.50.
   
   0.569
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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