| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KWZ73094.1 | KWZ73125.1 | HMPREF3198_01452 | HMPREF3198_01483 | Citrate (Si)-synthase; KEGG: mcu:HMPREF0573_10956 9.2e-158 gltA; type II citrate synthase K01647; Psort location: Cytoplasmic, score: 9.97. | Isocitrate dehydrogenase, NADP-dependent; KEGG: cfl:Cfla_2528 2.8e-181 isocitrate dehydrogenase K00031; Psort location: Cytoplasmic, score: 7.50; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.949 |
| KWZ73094.1 | KWZ73134.1 | HMPREF3198_01452 | HMPREF3198_01492 | Citrate (Si)-synthase; KEGG: mcu:HMPREF0573_10956 9.2e-158 gltA; type II citrate synthase K01647; Psort location: Cytoplasmic, score: 9.97. | KEGG: mcu:HMPREF0573_10281 6.5e-102 sdhB; succinate dehydrogenase/fumarate reductase iron-sulfur subunit K00240; Psort location: Cytoplasmic, score: 9.89. | 0.913 |
| KWZ73094.1 | KWZ73909.1 | HMPREF3198_01452 | HMPREF3198_01122 | Citrate (Si)-synthase; KEGG: mcu:HMPREF0573_10956 9.2e-158 gltA; type II citrate synthase K01647; Psort location: Cytoplasmic, score: 9.97. | KEGG: bcv:Bcav_1417 6.9e-114 3-isopropylmalate dehydrogenase K00052; Psort location: Cytoplasmic, score: 9.97. | 0.908 |
| KWZ73094.1 | KWZ74957.1 | HMPREF3198_01452 | HMPREF3198_00601 | Citrate (Si)-synthase; KEGG: mcu:HMPREF0573_10956 9.2e-158 gltA; type II citrate synthase K01647; Psort location: Cytoplasmic, score: 9.97. | MaoC-like protein; KEGG: cef:CE0913 0. fasA; fatty-acid synthase I K11533; Psort location: Cytoplasmic, score: 9.95. | 0.886 |
| KWZ73094.1 | acnA | HMPREF3198_01452 | HMPREF3198_02232 | Citrate (Si)-synthase; KEGG: mcu:HMPREF0573_10956 9.2e-158 gltA; type II citrate synthase K01647; Psort location: Cytoplasmic, score: 9.97. | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 0.996 |
| KWZ73094.1 | aspA | HMPREF3198_01452 | HMPREF3198_01412 | Citrate (Si)-synthase; KEGG: mcu:HMPREF0573_10956 9.2e-158 gltA; type II citrate synthase K01647; Psort location: Cytoplasmic, score: 9.97. | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.932 |
| KWZ73094.1 | kgd | HMPREF3198_01452 | HMPREF3198_01376 | Citrate (Si)-synthase; KEGG: mcu:HMPREF0573_10956 9.2e-158 gltA; type II citrate synthase K01647; Psort location: Cytoplasmic, score: 9.97. | KEGG: bcv:Bcav_1274 0. kgd; alpha-ketoglutarate decarboxylase; K00164 2-oxoglutarate dehydrogenase E1 component; Psort location: Cytoplasmic, score: 9.97. | 0.997 |
| KWZ73094.1 | ldh | HMPREF3198_01452 | HMPREF3198_01883 | Citrate (Si)-synthase; KEGG: mcu:HMPREF0573_10956 9.2e-158 gltA; type II citrate synthase K01647; Psort location: Cytoplasmic, score: 9.97. | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. | 0.892 |
| KWZ73094.1 | mdh | HMPREF3198_01452 | HMPREF3198_01479 | Citrate (Si)-synthase; KEGG: mcu:HMPREF0573_10956 9.2e-158 gltA; type II citrate synthase K01647; Psort location: Cytoplasmic, score: 9.97. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.937 |
| KWZ73094.1 | sucC | HMPREF3198_01452 | HMPREF3198_01630 | Citrate (Si)-synthase; KEGG: mcu:HMPREF0573_10956 9.2e-158 gltA; type II citrate synthase K01647; Psort location: Cytoplasmic, score: 9.97. | succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.963 |
| KWZ73125.1 | KWZ73094.1 | HMPREF3198_01483 | HMPREF3198_01452 | Isocitrate dehydrogenase, NADP-dependent; KEGG: cfl:Cfla_2528 2.8e-181 isocitrate dehydrogenase K00031; Psort location: Cytoplasmic, score: 7.50; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Citrate (Si)-synthase; KEGG: mcu:HMPREF0573_10956 9.2e-158 gltA; type II citrate synthase K01647; Psort location: Cytoplasmic, score: 9.97. | 0.949 |
| KWZ73125.1 | KWZ73134.1 | HMPREF3198_01483 | HMPREF3198_01492 | Isocitrate dehydrogenase, NADP-dependent; KEGG: cfl:Cfla_2528 2.8e-181 isocitrate dehydrogenase K00031; Psort location: Cytoplasmic, score: 7.50; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | KEGG: mcu:HMPREF0573_10281 6.5e-102 sdhB; succinate dehydrogenase/fumarate reductase iron-sulfur subunit K00240; Psort location: Cytoplasmic, score: 9.89. | 0.748 |
| KWZ73125.1 | KWZ73909.1 | HMPREF3198_01483 | HMPREF3198_01122 | Isocitrate dehydrogenase, NADP-dependent; KEGG: cfl:Cfla_2528 2.8e-181 isocitrate dehydrogenase K00031; Psort location: Cytoplasmic, score: 7.50; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | KEGG: bcv:Bcav_1417 6.9e-114 3-isopropylmalate dehydrogenase K00052; Psort location: Cytoplasmic, score: 9.97. | 0.840 |
| KWZ73125.1 | KWZ74957.1 | HMPREF3198_01483 | HMPREF3198_00601 | Isocitrate dehydrogenase, NADP-dependent; KEGG: cfl:Cfla_2528 2.8e-181 isocitrate dehydrogenase K00031; Psort location: Cytoplasmic, score: 7.50; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | MaoC-like protein; KEGG: cef:CE0913 0. fasA; fatty-acid synthase I K11533; Psort location: Cytoplasmic, score: 9.95. | 0.802 |
| KWZ73125.1 | acnA | HMPREF3198_01483 | HMPREF3198_02232 | Isocitrate dehydrogenase, NADP-dependent; KEGG: cfl:Cfla_2528 2.8e-181 isocitrate dehydrogenase K00031; Psort location: Cytoplasmic, score: 7.50; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 0.953 |
| KWZ73125.1 | aspA | HMPREF3198_01483 | HMPREF3198_01412 | Isocitrate dehydrogenase, NADP-dependent; KEGG: cfl:Cfla_2528 2.8e-181 isocitrate dehydrogenase K00031; Psort location: Cytoplasmic, score: 7.50; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.605 |
| KWZ73125.1 | kgd | HMPREF3198_01483 | HMPREF3198_01376 | Isocitrate dehydrogenase, NADP-dependent; KEGG: cfl:Cfla_2528 2.8e-181 isocitrate dehydrogenase K00031; Psort location: Cytoplasmic, score: 7.50; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | KEGG: bcv:Bcav_1274 0. kgd; alpha-ketoglutarate decarboxylase; K00164 2-oxoglutarate dehydrogenase E1 component; Psort location: Cytoplasmic, score: 9.97. | 0.958 |
| KWZ73125.1 | ldh | HMPREF3198_01483 | HMPREF3198_01883 | Isocitrate dehydrogenase, NADP-dependent; KEGG: cfl:Cfla_2528 2.8e-181 isocitrate dehydrogenase K00031; Psort location: Cytoplasmic, score: 7.50; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. | 0.908 |
| KWZ73125.1 | mdh | HMPREF3198_01483 | HMPREF3198_01479 | Isocitrate dehydrogenase, NADP-dependent; KEGG: cfl:Cfla_2528 2.8e-181 isocitrate dehydrogenase K00031; Psort location: Cytoplasmic, score: 7.50; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.922 |
| KWZ73125.1 | sucC | HMPREF3198_01483 | HMPREF3198_01630 | Isocitrate dehydrogenase, NADP-dependent; KEGG: cfl:Cfla_2528 2.8e-181 isocitrate dehydrogenase K00031; Psort location: Cytoplasmic, score: 7.50; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.918 |