close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
whiB-4Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA. (95 aa)    
Predicted Functional Partners:
sigA
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.803
whiB-2
Transcription factor WhiB; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
   
 0.802
KWZ72580.1
Hypothetical protein; KEGG: zga:zobellia_3774 2.6e-08 pelA2; pectate lyase, family PL1; Psort location: Cytoplasmic, score: 7.50.
  
     0.659
KWZ74793.1
KEGG: mcu:HMPREF0573_10554 1.3e-55 gpmB; phosphoglycerate mutase; Psort location: Cytoplasmic, score: 7.50.
  
     0.639
KWZ74479.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
  
     0.606
KWZ72913.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
  
     0.598
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
       0.588
KWZ72060.1
KEGG: cfi:Celf_2039 1.1e-44 lipid A biosynthesis acyltransferase; K02517 lipid A biosynthesis lauroyl acyltransferase; Psort location: Cytoplasmic, score: 7.50.
  
     0.561
KWZ75306.1
Beta-lactamase; KEGG: rca:Rcas_0624 3.2e-16 beta-lactamase; K01467 beta-lactamase.
  
     0.555
leuS
leucine--tRNA ligase; KEGG: mcu:HMPREF0573_11157 0. leuS; leucine--tRNA ligase K01869; Psort location: Cytoplasmic, score: 9.97; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
     0.530
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.