| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KWZ73139.1 | pheT | HMPREF3198_01497 | HMPREF3198_01230 | Hydrolase, P-loop family; KEGG: krh:KRH_06630 1.7e-33 alr; alanine racemase K01775; Psort location: Cytoplasmic, score: 7.50. | phenylalanine--tRNA ligase, beta subunit; KEGG: mcu:HMPREF0573_10030 5.7e-245 pheT; phenylalanine--tRNA ligase K01890; Psort location: Cytoplasmic, score: 9.97; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.423 |
| KWZ73139.1 | polA | HMPREF3198_01497 | HMPREF3198_02272 | Hydrolase, P-loop family; KEGG: krh:KRH_06630 1.7e-33 alr; alanine racemase K01775; Psort location: Cytoplasmic, score: 7.50. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.407 |
| KWZ73139.1 | tsaB | HMPREF3198_01497 | HMPREF3198_01496 | Hydrolase, P-loop family; KEGG: krh:KRH_06630 1.7e-33 alr; alanine racemase K01775; Psort location: Cytoplasmic, score: 7.50. | Universal bacterial protein YeaZ; KEGG: xce:Xcel_0675 3.3e-34 peptidase M22 glycoprotease; K14742 hypothetical protease; Psort location: Cytoplasmic, score: 7.50. | 0.992 |
| KWZ73139.1 | tsaD | HMPREF3198_01497 | HMPREF3198_01491 | Hydrolase, P-loop family; KEGG: krh:KRH_06630 1.7e-33 alr; alanine racemase K01775; Psort location: Cytoplasmic, score: 7.50. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.967 |
| KWZ73181.1 | tsaD | HMPREF3198_01540 | HMPREF3198_01491 | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.993 |
| asd | recO | HMPREF3198_00289 | HMPREF3198_01284 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.677 |
| asd | tsaD | HMPREF3198_00289 | HMPREF3198_01491 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.582 |
| gpsA | tsaD | HMPREF3198_01771 | HMPREF3198_01491 | NAD-dependent glycerol-3-phosphate dehydrogenase [NAD(P)+ ] protein; KEGG: kse:Ksed_10760 6.4e-63 glycerol-3-phosphate dehydrogenase K00057; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.573 |
| pheS | pheT | HMPREF3198_01231 | HMPREF3198_01230 | KEGG: cfi:Celf_1651 8.0e-136 phenylalanyl-tRNA synthetase subunit alpha; K01889 phenylalanyl-tRNA synthetase alpha chain; Psort location: Cytoplasmic, score: 10.00. | phenylalanine--tRNA ligase, beta subunit; KEGG: mcu:HMPREF0573_10030 5.7e-245 pheT; phenylalanine--tRNA ligase K01890; Psort location: Cytoplasmic, score: 9.97; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.999 |
| pheS | tsaD | HMPREF3198_01231 | HMPREF3198_01491 | KEGG: cfi:Celf_1651 8.0e-136 phenylalanyl-tRNA synthetase subunit alpha; K01889 phenylalanyl-tRNA synthetase alpha chain; Psort location: Cytoplasmic, score: 10.00. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.565 |
| pheS | ychF | HMPREF3198_01231 | HMPREF3198_00519 | KEGG: cfi:Celf_1651 8.0e-136 phenylalanyl-tRNA synthetase subunit alpha; K01889 phenylalanyl-tRNA synthetase alpha chain; Psort location: Cytoplasmic, score: 10.00. | GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.513 |
| pheT | KWZ73139.1 | HMPREF3198_01230 | HMPREF3198_01497 | phenylalanine--tRNA ligase, beta subunit; KEGG: mcu:HMPREF0573_10030 5.7e-245 pheT; phenylalanine--tRNA ligase K01890; Psort location: Cytoplasmic, score: 9.97; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | Hydrolase, P-loop family; KEGG: krh:KRH_06630 1.7e-33 alr; alanine racemase K01775; Psort location: Cytoplasmic, score: 7.50. | 0.423 |
| pheT | pheS | HMPREF3198_01230 | HMPREF3198_01231 | phenylalanine--tRNA ligase, beta subunit; KEGG: mcu:HMPREF0573_10030 5.7e-245 pheT; phenylalanine--tRNA ligase K01890; Psort location: Cytoplasmic, score: 9.97; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | KEGG: cfi:Celf_1651 8.0e-136 phenylalanyl-tRNA synthetase subunit alpha; K01889 phenylalanyl-tRNA synthetase alpha chain; Psort location: Cytoplasmic, score: 10.00. | 0.999 |
| pheT | polA | HMPREF3198_01230 | HMPREF3198_02272 | phenylalanine--tRNA ligase, beta subunit; KEGG: mcu:HMPREF0573_10030 5.7e-245 pheT; phenylalanine--tRNA ligase K01890; Psort location: Cytoplasmic, score: 9.97; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.897 |
| pheT | tsaD | HMPREF3198_01230 | HMPREF3198_01491 | phenylalanine--tRNA ligase, beta subunit; KEGG: mcu:HMPREF0573_10030 5.7e-245 pheT; phenylalanine--tRNA ligase K01890; Psort location: Cytoplasmic, score: 9.97; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.654 |
| pheT | ychF | HMPREF3198_01230 | HMPREF3198_00519 | phenylalanine--tRNA ligase, beta subunit; KEGG: mcu:HMPREF0573_10030 5.7e-245 pheT; phenylalanine--tRNA ligase K01890; Psort location: Cytoplasmic, score: 9.97; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.814 |
| polA | KWZ73139.1 | HMPREF3198_02272 | HMPREF3198_01497 | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Hydrolase, P-loop family; KEGG: krh:KRH_06630 1.7e-33 alr; alanine racemase K01775; Psort location: Cytoplasmic, score: 7.50. | 0.407 |
| polA | pheT | HMPREF3198_02272 | HMPREF3198_01230 | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | phenylalanine--tRNA ligase, beta subunit; KEGG: mcu:HMPREF0573_10030 5.7e-245 pheT; phenylalanine--tRNA ligase K01890; Psort location: Cytoplasmic, score: 9.97; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.897 |
| polA | recO | HMPREF3198_02272 | HMPREF3198_01284 | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.543 |
| polA | tsaD | HMPREF3198_02272 | HMPREF3198_01491 | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.572 |