| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KWZ72537.1 | alr | HMPREF3198_01895 | HMPREF3198_01498 | Penicillin-binding protein, transpeptidase domain protein; KEGG: mcu:HMPREF0573_11576 9.6e-124 peptidoglycan glycosyltransferase K03587; Psort location: CytoplasmicMembrane, score: 9.68. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.640 |
| KWZ72537.1 | ddl-2 | HMPREF3198_01895 | HMPREF3198_01772 | Penicillin-binding protein, transpeptidase domain protein; KEGG: mcu:HMPREF0573_11576 9.6e-124 peptidoglycan glycosyltransferase K03587; Psort location: CytoplasmicMembrane, score: 9.68. | D-ala D-ala ligase protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.706 |
| KWZ72537.1 | murD | HMPREF3198_01895 | HMPREF3198_01898 | Penicillin-binding protein, transpeptidase domain protein; KEGG: mcu:HMPREF0573_11576 9.6e-124 peptidoglycan glycosyltransferase K03587; Psort location: CytoplasmicMembrane, score: 9.68. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.913 |
| KWZ72537.1 | murF | HMPREF3198_01895 | HMPREF3198_01896 | Penicillin-binding protein, transpeptidase domain protein; KEGG: mcu:HMPREF0573_11576 9.6e-124 peptidoglycan glycosyltransferase K03587; Psort location: CytoplasmicMembrane, score: 9.68. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.965 |
| KWZ73139.1 | alr | HMPREF3198_01497 | HMPREF3198_01498 | Hydrolase, P-loop family; KEGG: krh:KRH_06630 1.7e-33 alr; alanine racemase K01775; Psort location: Cytoplasmic, score: 7.50. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.991 |
| KWZ73139.1 | glmS | HMPREF3198_01497 | HMPREF3198_01500 | Hydrolase, P-loop family; KEGG: krh:KRH_06630 1.7e-33 alr; alanine racemase K01775; Psort location: Cytoplasmic, score: 7.50. | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.573 |
| KWZ73139.1 | nnrD | HMPREF3198_01497 | HMPREF3198_01499 | Hydrolase, P-loop family; KEGG: krh:KRH_06630 1.7e-33 alr; alanine racemase K01775; Psort location: Cytoplasmic, score: 7.50. | Putative YjeF-like protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family. | 0.835 |
| KWZ73139.1 | rimI | HMPREF3198_01497 | HMPREF3198_01495 | Hydrolase, P-loop family; KEGG: krh:KRH_06630 1.7e-33 alr; alanine racemase K01775; Psort location: Cytoplasmic, score: 7.50. | KEGG: bcv:Bcav_3070 1.9e-22 ribosomal-protein-alanine acetyltransferase; K03789 ribosomal-protein-alanine N-acetyltransferase; Psort location: CytoplasmicMembrane, score: 9.55. | 0.836 |
| KWZ73139.1 | tsaB | HMPREF3198_01497 | HMPREF3198_01496 | Hydrolase, P-loop family; KEGG: krh:KRH_06630 1.7e-33 alr; alanine racemase K01775; Psort location: Cytoplasmic, score: 7.50. | Universal bacterial protein YeaZ; KEGG: xce:Xcel_0675 3.3e-34 peptidase M22 glycoprotease; K14742 hypothetical protease; Psort location: Cytoplasmic, score: 7.50. | 0.992 |
| ald | alr | HMPREF3198_00924 | HMPREF3198_01498 | KEGG: tbi:Tbis_0822 4.3e-121 alanine dehydrogenase; K00259 alanine dehydrogenase; Psort location: Extracellular, score: 9.60; Belongs to the AlaDH/PNT family. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.811 |
| alr | KWZ72537.1 | HMPREF3198_01498 | HMPREF3198_01895 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Penicillin-binding protein, transpeptidase domain protein; KEGG: mcu:HMPREF0573_11576 9.6e-124 peptidoglycan glycosyltransferase K03587; Psort location: CytoplasmicMembrane, score: 9.68. | 0.640 |
| alr | KWZ73139.1 | HMPREF3198_01498 | HMPREF3198_01497 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Hydrolase, P-loop family; KEGG: krh:KRH_06630 1.7e-33 alr; alanine racemase K01775; Psort location: Cytoplasmic, score: 7.50. | 0.991 |
| alr | ald | HMPREF3198_01498 | HMPREF3198_00924 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | KEGG: tbi:Tbis_0822 4.3e-121 alanine dehydrogenase; K00259 alanine dehydrogenase; Psort location: Extracellular, score: 9.60; Belongs to the AlaDH/PNT family. | 0.811 |
| alr | ddl-2 | HMPREF3198_01498 | HMPREF3198_01772 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | D-ala D-ala ligase protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.840 |
| alr | glmS | HMPREF3198_01498 | HMPREF3198_01500 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.713 |
| alr | murD | HMPREF3198_01498 | HMPREF3198_01898 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.661 |
| alr | murF | HMPREF3198_01498 | HMPREF3198_01896 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.975 |
| alr | nnrD | HMPREF3198_01498 | HMPREF3198_01499 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Putative YjeF-like protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family. | 0.653 |
| alr | rimI | HMPREF3198_01498 | HMPREF3198_01495 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | KEGG: bcv:Bcav_3070 1.9e-22 ribosomal-protein-alanine acetyltransferase; K03789 ribosomal-protein-alanine N-acetyltransferase; Psort location: CytoplasmicMembrane, score: 9.55. | 0.813 |
| alr | tsaB | HMPREF3198_01498 | HMPREF3198_01496 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Universal bacterial protein YeaZ; KEGG: xce:Xcel_0675 3.3e-34 peptidase M22 glycoprotease; K14742 hypothetical protease; Psort location: Cytoplasmic, score: 7.50. | 0.778 |