STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KWZ73164.15'-nucleotidase protein; KEGG: ahe:Arch_0203 2.4e-111 LPXTG-motif cell wall anchor domain-containing protein; K01081 5'-nucleotidase; Psort location: Cellwall, score: 9.20; Belongs to the 5'-nucleotidase family. (674 aa)    
Predicted Functional Partners:
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.970
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
    
 0.921
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Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
    
 0.920
deoD
KEGG: ckp:ckrop_0402 6.7e-84 deoD; purine nucleoside phosphorylase K03784; Psort location: Cytoplasmic, score: 9.67.
    
  0.915
tmk
dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
 
 
  0.871
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
 0.861
KWZ74398.1
LPXTG-motif protein cell wall anchor domain protein; KEGG: crd:CRES_1125 6.8e-91 nucI; 5-nucleotidase; Psort location: Cellwall, score: 9.20; Belongs to the 5'-nucleotidase family.
 
  
0.861
KWZ72283.1
LPXTG-motif protein cell wall anchor domain protein; KEGG: bmd:BMD_3960 1.3e-08 phosphatase/fibronectin domain-containing protein.
  
 
 0.860
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
   
 
 0.853
KWZ72917.1
Putative dGTPase; KEGG: cfl:Cfla_2171 7.4e-117 deoxyguanosinetriphosphate triphosphohydrolase; K01129 dGTPase; Psort location: Cytoplasmic, score: 7.50; Belongs to the dGTPase family. Type 2 subfamily.
    
  0.851
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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