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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KWZ73212.1LPXTG-motif protein cell wall anchor domain protein; KEGG: bme:BMEII0655 1.5e-132 alkaline phosphatase K01077. (836 aa)    
Predicted Functional Partners:
KWZ73164.1
5'-nucleotidase protein; KEGG: ahe:Arch_0203 2.4e-111 LPXTG-motif cell wall anchor domain-containing protein; K01081 5'-nucleotidase; Psort location: Cellwall, score: 9.20; Belongs to the 5'-nucleotidase family.
    
 0.816
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.805
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.783
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
 0.779
tmk
dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
   
 
  0.777
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
    
  0.774
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Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
    
 0.767
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
 0.755
KWZ74941.1
Hydrolase, NUDIX family; KEGG: cai:Caci_7803 1.0e-48 NUDIX hydrolase; K03426 NAD+ diphosphatase; Psort location: Cytoplasmic, score: 7.50.
    
  0.754
KWZ72519.1
Competence/damage-inducible protein CinA domain protein; KEGG: rsp:RSP_1822 1.1e-14 NH(3)-dependent NAD(+) synthetase K03743; Belongs to the CinA family.
   
 
  0.754
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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