STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadENAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (682 aa)    
Predicted Functional Partners:
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.992
nadK
Putative inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
    
 0.966
KWZ75627.1
KEGG: mcu:HMPREF0573_10471 2.1e-80 npdA; Sir2 family NAD-dependent deacetylase; Psort location: Cytoplasmic, score: 7.50.
    
 0.960
lpdA
Dihydrolipoyl dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
    
 0.943
ald
KEGG: tbi:Tbis_0822 4.3e-121 alanine dehydrogenase; K00259 alanine dehydrogenase; Psort location: Extracellular, score: 9.60; Belongs to the AlaDH/PNT family.
  
 
  0.938
KWZ74941.1
Hydrolase, NUDIX family; KEGG: cai:Caci_7803 1.0e-48 NUDIX hydrolase; K03426 NAD+ diphosphatase; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.921
rsfS
Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
    
  0.921
KWZ72515.1
DNA-binding helix-turn-helix protein; KEGG: mxa:MXAN_0261 6.6e-05 transcriptional regulator; K02806 PTS system, nitrogen regulatory IIA component; Psort location: Cytoplasmic, score: 7.50.
    
 0.920
KWZ74368.1
Aldehyde dehydrogenase family protein; KEGG: mcu:HMPREF0573_11678 0. L-proline dehydrogenase / delta-1-pyrroline-5-carboxylate dehydrogenase K13821; Psort location: Cytoplasmic, score: 9.95.
  
 
  0.913
KWZ74957.1
MaoC-like protein; KEGG: cef:CE0913 0. fasA; fatty-acid synthase I K11533; Psort location: Cytoplasmic, score: 9.95.
  
 
 0.904
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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