| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KWZ72546.1 | KWZ72860.1 | HMPREF3198_01904 | HMPREF3198_01642 | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50; Belongs to the multicopper oxidase YfiH/RL5 family. | Isochorismatase family protein; KEGG: cfi:Celf_3076 5.6e-64 isochorismatase hydrolase; K08281 nicotinamidase/pyrazinamidase; Psort location: Cytoplasmic, score: 9.97. | 0.612 |
| KWZ72860.1 | KWZ72546.1 | HMPREF3198_01642 | HMPREF3198_01904 | Isochorismatase family protein; KEGG: cfi:Celf_3076 5.6e-64 isochorismatase hydrolase; K08281 nicotinamidase/pyrazinamidase; Psort location: Cytoplasmic, score: 9.97. | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50; Belongs to the multicopper oxidase YfiH/RL5 family. | 0.612 |
| KWZ72860.1 | KWZ73167.1 | HMPREF3198_01642 | HMPREF3198_01526 | Isochorismatase family protein; KEGG: cfi:Celf_3076 5.6e-64 isochorismatase hydrolase; K08281 nicotinamidase/pyrazinamidase; Psort location: Cytoplasmic, score: 9.97. | Shikimate kinase; KEGG: cfl:Cfla_0786 2.0e-45 thermoresistant glucokinase family carbohydrate kinase K00851; Psort location: Cytoplasmic, score: 7.50. | 0.884 |
| KWZ72860.1 | KWZ73194.1 | HMPREF3198_01642 | HMPREF3198_01553 | Isochorismatase family protein; KEGG: cfi:Celf_3076 5.6e-64 isochorismatase hydrolase; K08281 nicotinamidase/pyrazinamidase; Psort location: Cytoplasmic, score: 9.97. | KEGG: pfr:PFREUD_00770 4.8e-129 gpsA; glycerol-3-phosphate dehydrogenase [NAD(P)+] K00057; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.557 |
| KWZ72860.1 | KWZ74935.1 | HMPREF3198_01642 | HMPREF3198_00579 | Isochorismatase family protein; KEGG: cfi:Celf_3076 5.6e-64 isochorismatase hydrolase; K08281 nicotinamidase/pyrazinamidase; Psort location: Cytoplasmic, score: 9.97. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.986 |
| KWZ72860.1 | ahpC | HMPREF3198_01642 | HMPREF3198_01458 | Isochorismatase family protein; KEGG: cfi:Celf_3076 5.6e-64 isochorismatase hydrolase; K08281 nicotinamidase/pyrazinamidase; Psort location: Cytoplasmic, score: 9.97. | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | 0.517 |
| KWZ72860.1 | gpsA | HMPREF3198_01642 | HMPREF3198_01771 | Isochorismatase family protein; KEGG: cfi:Celf_3076 5.6e-64 isochorismatase hydrolase; K08281 nicotinamidase/pyrazinamidase; Psort location: Cytoplasmic, score: 9.97. | NAD-dependent glycerol-3-phosphate dehydrogenase [NAD(P)+ ] protein; KEGG: kse:Ksed_10760 6.4e-63 glycerol-3-phosphate dehydrogenase K00057; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | 0.557 |
| KWZ72860.1 | metG | HMPREF3198_01642 | HMPREF3198_01641 | Isochorismatase family protein; KEGG: cfi:Celf_3076 5.6e-64 isochorismatase hydrolase; K08281 nicotinamidase/pyrazinamidase; Psort location: Cytoplasmic, score: 9.97. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.532 |
| KWZ72860.1 | nadE | HMPREF3198_01642 | HMPREF3198_01623 | Isochorismatase family protein; KEGG: cfi:Celf_3076 5.6e-64 isochorismatase hydrolase; K08281 nicotinamidase/pyrazinamidase; Psort location: Cytoplasmic, score: 9.97. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.597 |
| KWZ72860.1 | rpoB | HMPREF3198_01642 | HMPREF3198_01589 | Isochorismatase family protein; KEGG: cfi:Celf_3076 5.6e-64 isochorismatase hydrolase; K08281 nicotinamidase/pyrazinamidase; Psort location: Cytoplasmic, score: 9.97. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.514 |
| KWZ72860.1 | rpsL | HMPREF3198_01642 | HMPREF3198_01587 | Isochorismatase family protein; KEGG: cfi:Celf_3076 5.6e-64 isochorismatase hydrolase; K08281 nicotinamidase/pyrazinamidase; Psort location: Cytoplasmic, score: 9.97. | Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. | 0.544 |
| KWZ73167.1 | KWZ72860.1 | HMPREF3198_01526 | HMPREF3198_01642 | Shikimate kinase; KEGG: cfl:Cfla_0786 2.0e-45 thermoresistant glucokinase family carbohydrate kinase K00851; Psort location: Cytoplasmic, score: 7.50. | Isochorismatase family protein; KEGG: cfi:Celf_3076 5.6e-64 isochorismatase hydrolase; K08281 nicotinamidase/pyrazinamidase; Psort location: Cytoplasmic, score: 9.97. | 0.884 |
| KWZ73194.1 | KWZ72860.1 | HMPREF3198_01553 | HMPREF3198_01642 | KEGG: pfr:PFREUD_00770 4.8e-129 gpsA; glycerol-3-phosphate dehydrogenase [NAD(P)+] K00057; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | Isochorismatase family protein; KEGG: cfi:Celf_3076 5.6e-64 isochorismatase hydrolase; K08281 nicotinamidase/pyrazinamidase; Psort location: Cytoplasmic, score: 9.97. | 0.557 |
| KWZ74935.1 | KWZ72860.1 | HMPREF3198_00579 | HMPREF3198_01642 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Isochorismatase family protein; KEGG: cfi:Celf_3076 5.6e-64 isochorismatase hydrolase; K08281 nicotinamidase/pyrazinamidase; Psort location: Cytoplasmic, score: 9.97. | 0.986 |
| KWZ74935.1 | nadE | HMPREF3198_00579 | HMPREF3198_01623 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.774 |
| ahpC | KWZ72860.1 | HMPREF3198_01458 | HMPREF3198_01642 | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | Isochorismatase family protein; KEGG: cfi:Celf_3076 5.6e-64 isochorismatase hydrolase; K08281 nicotinamidase/pyrazinamidase; Psort location: Cytoplasmic, score: 9.97. | 0.517 |
| ahpC | rpoB | HMPREF3198_01458 | HMPREF3198_01589 | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.563 |
| ahpC | rpsL | HMPREF3198_01458 | HMPREF3198_01587 | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. | 0.425 |
| gpsA | KWZ72860.1 | HMPREF3198_01771 | HMPREF3198_01642 | NAD-dependent glycerol-3-phosphate dehydrogenase [NAD(P)+ ] protein; KEGG: kse:Ksed_10760 6.4e-63 glycerol-3-phosphate dehydrogenase K00057; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. | Isochorismatase family protein; KEGG: cfi:Celf_3076 5.6e-64 isochorismatase hydrolase; K08281 nicotinamidase/pyrazinamidase; Psort location: Cytoplasmic, score: 9.97. | 0.557 |
| metG | KWZ72860.1 | HMPREF3198_01641 | HMPREF3198_01642 | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Isochorismatase family protein; KEGG: cfi:Celf_3076 5.6e-64 isochorismatase hydrolase; K08281 nicotinamidase/pyrazinamidase; Psort location: Cytoplasmic, score: 9.97. | 0.532 |