STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaE2DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1029 aa)    
Predicted Functional Partners:
holA
KEGG: bcv:Bcav_1739 1.2e-75 DNA polymerase III subunit delta; K02340 DNA polymerase III subunit delta; Psort location: Cellwall, score: 8.19.
  
 0.965
KWZ74693.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 0.962
KWZ72768.1
Hypothetical protein; KEGG: sen:SACE_6661 1.4e-49 DNA-directed DNA polymerase K14161; Psort location: Cytoplasmic, score: 7.50.
 
  
 0.957
KWZ72770.1
Hypothetical protein.
 
  
 0.947
KWZ73128.1
Hypothetical protein; KEGG: mcu:HMPREF0573_11531 1.4e-28 dnaQ; DNA polymerase III subunit epsilon K02342; Psort location: Cytoplasmic, score: 7.50.
  
 0.936
KWZ75212.1
KEGG: iva:Isova_2736 4.7e-170 DNA polymerase III subunits gamma and tau; K02343 DNA polymerase III subunit gamma/tau; Psort location: Cytoplasmic, score: 9.97.
  
 0.926
KWZ72157.1
GIY-YIG catalytic domain protein; KEGG: bcv:Bcav_1900 1.8e-106 hypothetical protein; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 9.67.
 
  
 0.880
dinB
ImpB/MucB/SamB family protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
 
  
 0.867
KWZ75030.1
KEGG: iva:Isova_0427 6.0e-115 DNA polymerase III, delta prime subunit; K02341 DNA polymerase III subunit delta'; Psort location: Cytoplasmic, score: 9.97.
  
 0.838
KWZ74677.1
KEGG: shn:Shewana3_3590 5.8e-14 single-strand binding protein K03111; Psort location: Cytoplasmic, score: 9.67.
  
 
 0.820
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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