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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KWZ72768.1Hypothetical protein; KEGG: sen:SACE_6661 1.4e-49 DNA-directed DNA polymerase K14161; Psort location: Cytoplasmic, score: 7.50. (427 aa)    
Predicted Functional Partners:
KWZ72770.1
Hypothetical protein.
 
  
 0.992
KWZ74693.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.984
dnaE2
DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.
 
  
 0.957
KWZ72767.1
Protein, SNF2 family; KEGG: mph:MLP_35040 1.9e-132 putative helicase; Psort location: CytoplasmicMembrane, score: 8.16.
   
  0.877
lexA
Repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
  
 
 0.797
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.793
KWZ72769.1
Hypothetical protein; KEGG: fal:FRAAL2179 7.9e-09 DNA-directed DNA polymerase K00961; Psort location: CytoplasmicMembrane, score: 9.55.
       0.773
KWZ75060.1
Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: cgo:Corgl_1656 1.4e-76 peptidoglycan glycosyltransferase; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family.
  
 
 0.739
KWZ72541.1
Cell cycle protein, FtsW/RodA/SpoVE family; KEGG: kfl:Kfla_2886 3.4e-57 cell division protein FtsW; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family.
   
 
 0.721
KWZ74867.1
Putative FK506-binding protein; KEGG: xce:Xcel_2669 6.1e-42 peptidylprolyl isomerase FKBP-type; K01802 peptidylprolyl isomerase; Psort location: Cytoplasmic, score: 9.67.
    
   0.684
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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