STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
KWZ72775.1Biotin-requiring enzyme; KEGG: cva:CVAR_1123 3.2e-35 sucB; dihydrolipoamide acyltransferase K00658; Psort location: Cytoplasmic, score: 9.67. (126 aa)    
Predicted Functional Partners:
lpdA
Dihydrolipoyl dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
 0.996
kgd
KEGG: bcv:Bcav_1274 0. kgd; alpha-ketoglutarate decarboxylase; K00164 2-oxoglutarate dehydrogenase E1 component; Psort location: Cytoplasmic, score: 9.97.
 0.986
aceE
Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 
 0.852
KWZ73094.1
Citrate (Si)-synthase; KEGG: mcu:HMPREF0573_10956 9.2e-158 gltA; type II citrate synthase K01647; Psort location: Cytoplasmic, score: 9.97.
  
 0.814
prs
Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.741
sucC
succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.734
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.632
KWZ74816.1
KEGG: ahe:Arch_0299 3.0e-239 NADH-quinone oxidoreductase subunit G; K00336 NADH-quinone oxidoreductase subunit G; Psort location: Cytoplasmic, score: 9.97.
  
  0.601
KWZ74742.1
FtsK/SpoIIIE family protein; KEGG: ppo:PPM_p0073 6.6e-17 topB; DNA topoisomerase III; Psort location: CytoplasmicMembrane, score: 10.00.
    
 
 0.586
atpA
ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
   
 0.585
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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