STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KWZ72678.1[glutamate--ammonia-ligase] adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal tra [...] (983 aa)    
Predicted Functional Partners:
KWZ72679.1
Glutamine synthetase, beta-grasp domain protein; KEGG: bcv:Bcav_1849 3.3e-162 glutamine synthetase, type I; K01915 glutamine synthetase; Psort location: Cytoplasmic, score: 9.97.
     
 0.947
glnA
KEGG: ske:Sked_15370 1.6e-194 L-glutamine synthetase K01915; Psort location: Cytoplasmic, score: 9.97.
 
   
 0.913
KWZ72677.1
KEGG: mcu:HMPREF0573_11598 1.1e-44 gpmB2; phosphoglycerate mutase K15634; Belongs to the phosphoglycerate mutase family.
       0.799
KWZ72680.1
SPFH/Band 7/PHB domain protein; KEGG: reh:H16_A2036 3.8e-49 h16_A2036; membrane protease subunits, stomatin/prohibitin homologs; Psort location: Cytoplasmic, score: 7.50.
       0.773
KWZ72682.1
KEGG: cfi:Celf_1721 1.3e-64 ABC transporter-like protein; K02013 iron complex transport system ATP-binding protein; Psort location: CytoplasmicMembrane, score: 8.78.
       0.761
KWZ72681.1
Nodulation efficiency protein D; Psort location: CytoplasmicMembrane, score: 9.55.
       0.748
KWZ72469.1
KEGG: sma:SAV_2649 9.5e-32 glnD; PII uridylyl-transferase K00990; Psort location: Cytoplasmic, score: 7.50.
     
 0.719
KWZ72130.1
KEGG: bcv:Bcav_1962 4.9e-88 3'-5' exonuclease; K03684 ribonuclease D; Psort location: Cytoplasmic, score: 9.97.
  
     0.695
KWZ72141.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
  
     0.685
KWZ72124.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
  
     0.659
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.