STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (271 aa)    
Predicted Functional Partners:
KWZ74368.1
Aldehyde dehydrogenase family protein; KEGG: mcu:HMPREF0573_11678 0. L-proline dehydrogenase / delta-1-pyrroline-5-carboxylate dehydrogenase K13821; Psort location: Cytoplasmic, score: 9.95.
   
 0.970
proA
Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 
 0.936
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 
 0.935
KWZ72459.1
KEGG: apb:SAR116_2479 2.9e-10 major facilitator superfamily protein; Psort location: CytoplasmicMembrane, score: 10.00.
       0.773
leuD
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
     
 0.760
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
     
 0.749
KWZ74538.1
Putative adenylosuccinate lyase; Psort location: Cytoplasmic, score: 7.50.
     
 0.715
KWZ74973.1
KEGG: aai:AARI_26540 2.9e-138 gabD; succinate-semialdehyde dehydrogenase K00135; Psort location: Cytoplasmic, score: 9.97.
   
 
 0.665
mmsA
KEGG: pak:HMPREF0675_3499 1.6e-155 mmsA; methylmalonate-semialdehyde dehydrogenase (acylating) K00140; Psort location: Cytoplasmic, score: 9.97.
   
 
 0.665
KWZ72692.1
KEGG: msm:MSMEG_0582 3.2e-148 succinate-semialdehyde dehydrogenase; K00135 succinate-semialdehyde dehydrogenase (NADP+); Psort location: Cytoplasmic, score: 9.64.
   
 
 0.665
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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