STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
KWZ72464.1Protein FolC; KEGG: ahe:Arch_0554 3.0e-129 bifunctional folylpolyglutamate synthase/dihydrofolate synthase K11754; Psort location: Cytoplasmic, score: 7.50. (559 aa)    
Predicted Functional Partners:
folP
KEGG: cms:CMS_0101 8.4e-61 dihydropteroate synthase; K00796 dihydropteroate synthase; Psort location: Cytoplasmic, score: 7.50.
 
 0.990
KWZ74785.1
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
  
 0.940
KWZ72465.1
KEGG: cga:Celgi_2121 4.3e-41 Nucleoside-diphosphate kinase; K00940 nucleoside-diphosphate kinase; Psort location: Cytoplasmic, score: 9.97; Belongs to the NDK family.
  
    0.766
folE
GTP cyclohydrolase I; KEGG: adg:Adeg_0594 1.6e-59 folE; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.708
KWZ74976.1
Dihydrofolate reductase; KEGG: mcu:HMPREF0573_10015 5.3e-36 putative dihydrofolate reductase; K00287 dihydrofolate reductase.
     
 0.679
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.662
smc
Putative segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.
       0.633
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.629
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
   
 
 0.602
valS
Anticodon-binding domain protein; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner.
  
  
 0.566
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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