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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (329 aa)    
Predicted Functional Partners:
KWZ73094.1
Citrate (Si)-synthase; KEGG: mcu:HMPREF0573_10956 9.2e-158 gltA; type II citrate synthase K01647; Psort location: Cytoplasmic, score: 9.97.
  
 0.983
pyk
Pyruvate kinase; KEGG: bcv:Bcav_2215 5.6e-183 pyruvate kinase K00873; Psort location: Cytoplasmic, score: 7.50.
  
 0.983
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
   
 
 0.967
pgi
KEGG: paz:TIA2EST2_10330 5.9e-211 pgi; glucose-6-phosphate isomerase K01810; Psort location: Cytoplasmic, score: 9.97; Belongs to the GPI family.
  
 
 0.960
KWZ74836.1
Putative aspartate transaminase; KEGG: mcu:HMPREF0573_11145 2.9e-154 aspC; aspartate transaminase.
  
 0.952
aceE
Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
 0.941
KWZ74990.1
NAD-dependent malic enzyme; KEGG: iva:Isova_1566 2.5e-155 malic protein NAD-binding protein; K00027 malate dehydrogenase (oxaloacetate-decarboxylating); Psort location: Cytoplasmic, score: 7.50.
  
 0.940
pflB
KEGG: ahe:Arch_0430 0. formate acetyltransferase K00656; Psort location: Cytoplasmic, score: 9.97.
   
 
 0.939
KWZ72631.1
Transketolase; KEGG: mcu:HMPREF0573_11615 3.9e-237 tkt; transketolase K00615; Psort location: Cytoplasmic, score: 7.50; Belongs to the transketolase family.
   
 0.939
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
   
 0.938
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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