STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KWZ72527.1LysM domain protein; KEGG: nth:Nther_0484 2.2e-06 cell wall hydrolase SleB; K01449 N-acetylmuramoyl-L-alanine amidase; Psort location: CytoplasmicMembrane, score: 9.55. (113 aa)    
Predicted Functional Partners:
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
    
  0.806
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.788
KWZ73048.1
Hypothetical protein; KEGG: bha:BH1667 0.0087 aroE; 3-phosphoshikimate 1-carboxyvinyltransferase K00800.
   
 
 0.705
lexA
Repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
  
  
 0.638
nrdR
Putative transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
       0.613
KWZ75570.1
Hypothetical protein; KEGG: mmw:Mmwyl1_1672 0.0022 beta strand repeat-containing protein; Psort location: CytoplasmicMembrane, score: 9.36.
   
   0.460
KWZ72296.1
LPXTG-motif protein cell wall anchor domain protein; KEGG: bbi:BBIF_1734 0.00025 sialidase; K01186 sialidase-1; Psort location: Cellwall, score: 9.20.
   
   0.460
KWZ72251.1
Signal peptide protein, YSIRK family.
   
   0.460
KWZ72187.1
LPXTG-motif protein cell wall anchor domain protein; KEGG: isc:IscW_ISCW000348 5.7e-08 secreted mucin MUC17, putative; Psort location: Cellwall, score: 9.97.
   
   0.460
crgA
Septation inhibitor domain protein; Involved in cell division; Belongs to the CrgA family.
  
     0.450
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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