Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
lipALipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (342 aa)    
Predicted Functional Partners:
lipB
Lipoyl(octanoyl) transferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
 
 0.999
lpdA
Dihydrolipoyl dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
  
 0.688
sucB
KEGG: ahe:Arch_0735 2.8e-149 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; K00658 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase); Psort location: Cytoplasmic, score: 9.97.
 
 
 0.603
kgd
KEGG: bcv:Bcav_1274 0. kgd; alpha-ketoglutarate decarboxylase; K00164 2-oxoglutarate dehydrogenase E1 component; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.572
KWZ73255.1
KEGG: xce:Xcel_0693 1.6e-107 phosphate acetyltransferase K13788; Psort location: Cytoplasmic, score: 7.50.
      
 0.494
KWZ72775.1
Biotin-requiring enzyme; KEGG: cva:CVAR_1123 3.2e-35 sucB; dihydrolipoamide acyltransferase K00658; Psort location: Cytoplasmic, score: 9.67.
 
 
 0.492
KWZ72559.1
Transporter, dicarboxylate/amino acid:cation Na+/H+ symporter family protein; KEGG: ctu:CTU_37370 1.9e-10 gltP; glutamate/aspartate:proton symporter K11102; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
       0.485
KWZ72561.1
KEGG: cfl:Cfla_1616 2.6e-27 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; K02501 glutamine amidotransferase; Psort location: Cytoplasmic, score: 7.50.
     
 0.478
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
  
 0.449
menG
Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
 
    
 0.430
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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