STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
addAdenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. (333 aa)    
Predicted Functional Partners:
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
 
 0.667
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
  
  
 0.631
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.557
deoD
KEGG: ckp:ckrop_0402 6.7e-84 deoD; purine nucleoside phosphorylase K03784; Psort location: Cytoplasmic, score: 9.67.
    
 0.546
rpmB
Ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
       0.542
KWZ73164.1
5'-nucleotidase protein; KEGG: ahe:Arch_0203 2.4e-111 LPXTG-motif cell wall anchor domain-containing protein; K01081 5'-nucleotidase; Psort location: Cellwall, score: 9.20; Belongs to the 5'-nucleotidase family.
    
 0.512
KWZ74398.1
LPXTG-motif protein cell wall anchor domain protein; KEGG: crd:CRES_1125 6.8e-91 nucI; 5-nucleotidase; Psort location: Cellwall, score: 9.20; Belongs to the 5'-nucleotidase family.
    
 0.511
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.