STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proAGlutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (420 aa)    
Predicted Functional Partners:
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 0.999
KWZ74368.1
Aldehyde dehydrogenase family protein; KEGG: mcu:HMPREF0573_11678 0. L-proline dehydrogenase / delta-1-pyrroline-5-carboxylate dehydrogenase K13821; Psort location: Cytoplasmic, score: 9.95.
    
 0.953
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
 
 
 0.936
purQ
Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]
   
 
 0.933
KWZ72679.1
Glutamine synthetase, beta-grasp domain protein; KEGG: bcv:Bcav_1849 3.3e-162 glutamine synthetase, type I; K01915 glutamine synthetase; Psort location: Cytoplasmic, score: 9.97.
     
 0.926
glnA
KEGG: ske:Sked_15370 1.6e-194 L-glutamine synthetase K01915; Psort location: Cytoplasmic, score: 9.97.
     
 0.919
KWZ75196.1
KEGG: mcu:HMPREF0573_10901 6.2e-168 gdh; glutamate dehydrogenase K00262; Psort location: Cytoplasmic, score: 9.97; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.918
atpA
ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
 
    
 0.865
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
  
 0.790
KWZ72693.1
KEGG: mlu:Mlut_00880 4.5e-133 glutamate dehydrogenase/leucine dehydrogenase K00261; Psort location: Cytoplasmic, score: 9.97; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.765
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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