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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KWZ72615.1AMP-binding enzyme; KEGG: bcv:Bcav_2594 1.8e-147 AMP-dependent synthetase and ligase; K01897 long-chain acyl-CoA synthetase; Psort location: CytoplasmicMembrane, score: 8.78. (602 aa)    
Predicted Functional Partners:
KWZ74957.1
MaoC-like protein; KEGG: cef:CE0913 0. fasA; fatty-acid synthase I K11533; Psort location: Cytoplasmic, score: 9.95.
  
 0.975
KWZ72529.1
Putative CoA ligase; KEGG: mcu:HMPREF0573_11567 3.2e-139 lcfA; putative long-subunit-fatty-acid--CoA ligase K01897; Psort location: Cytoplasmic, score: 9.97.
 
 
 
0.820
rplE
Ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
    
   0.714
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
  0.711
rplR
Ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
    
   0.675
KWZ74376.1
KEGG: paw:PAZ_c23040 1.6e-144 acdA; acyl-CoA dehydrogenase; Psort location: Cytoplasmic, score: 9.67.
  
 0.668
KWZ74663.1
Putative acetyl esterase; KEGG: ahe:Arch_1364 4.7e-67 alpha/beta hydrolase; K01066 esterase / lipase; Psort location: Cytoplasmic, score: 9.67.
   
 
  0.553
KWZ73930.1
Hydrolase, alpha/beta domain protein; KEGG: cnc:CNE_2c12200 1.2e-29 estB; esterase EstB; Psort location: CytoplasmicMembrane, score: 8.16.
   
 
  0.553
KWZ72616.1
Putative methylated-DNA--[protein]-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
       0.542
KWZ72556.1
AMP-binding enzyme; KEGG: ahe:Arch_1447 1.2e-77 AMP-dependent synthetase and ligase; K00666 fatty-acyl-CoA synthase; Psort location: Cytoplasmic, score: 9.97.
 
 
0.540
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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