STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cas1eCRISPR-associated endonuclease Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (314 aa)    
Predicted Functional Partners:
cas2e
CRISPR-associated endoribonuclease Cas2; Psort location: Cytoplasmic, score: 7.50.
 
 
 0.999
KWZ72272.1
CRISPR-associated helicase Cas3; KEGG: mph:MLP_28580 3.7e-05 putative ATP-dependent helicase K03724; Psort location: Cytoplasmic, score: 7.50.
 
  
 0.967
KWZ72276.1
CRISPR system CASCADE complex protein CasC; Psort location: Cytoplasmic, score: 7.50.
 
  
 0.941
cas5e
CRISPR system CASCADE complex protein CasD.
 
  
 0.935
KWZ72273.1
CRISPR associated protein; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.884
KWZ74930.1
DNA-binding protein HB1; KEGG: apb:SAR116_0125 4.2e-11 histone family protein DNA-binding protein K03530; Psort location: Cytoplasmic, score: 9.97; Belongs to the bacterial histone-like protein family.
    
   0.710
KWZ72274.1
Putative CRISPR system CASCADE complex protein CasA.
  
  
 0.697
casB
CRISPR system CASCADE complex protein CasB; Psort location: Cytoplasmic, score: 7.50.
       0.500
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.