| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KWZ72064.1 | apt | HMPREF3198_02162 | HMPREF3198_02169 | DNA-binding regulatory protein, YebC/PmpR family; KEGG: rdn:HMPREF0733_12022 5.2e-77 glucose-1-phosphate adenylyltransferase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.516 |
| KWZ72064.1 | ruvA | HMPREF3198_02162 | HMPREF3198_02164 | DNA-binding regulatory protein, YebC/PmpR family; KEGG: rdn:HMPREF0733_12022 5.2e-77 glucose-1-phosphate adenylyltransferase. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.757 |
| KWZ72064.1 | ruvB | HMPREF3198_02162 | HMPREF3198_02165 | DNA-binding regulatory protein, YebC/PmpR family; KEGG: rdn:HMPREF0733_12022 5.2e-77 glucose-1-phosphate adenylyltransferase. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.758 |
| KWZ72064.1 | ruvC | HMPREF3198_02162 | HMPREF3198_02163 | DNA-binding regulatory protein, YebC/PmpR family; KEGG: rdn:HMPREF0733_12022 5.2e-77 glucose-1-phosphate adenylyltransferase. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.833 |
| KWZ72064.1 | secD | HMPREF3198_02162 | HMPREF3198_02167 | DNA-binding regulatory protein, YebC/PmpR family; KEGG: rdn:HMPREF0733_12022 5.2e-77 glucose-1-phosphate adenylyltransferase. | Export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.572 |
| KWZ72064.1 | secF | HMPREF3198_02162 | HMPREF3198_02168 | DNA-binding regulatory protein, YebC/PmpR family; KEGG: rdn:HMPREF0733_12022 5.2e-77 glucose-1-phosphate adenylyltransferase. | Export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.589 |
| KWZ72064.1 | tig | HMPREF3198_02162 | HMPREF3198_01805 | DNA-binding regulatory protein, YebC/PmpR family; KEGG: rdn:HMPREF0733_12022 5.2e-77 glucose-1-phosphate adenylyltransferase. | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.472 |
| KWZ72064.1 | yajC | HMPREF3198_02162 | HMPREF3198_02166 | DNA-binding regulatory protein, YebC/PmpR family; KEGG: rdn:HMPREF0733_12022 5.2e-77 glucose-1-phosphate adenylyltransferase. | Preprotein translocase, YajC subunit; KEGG: mel:Metbo_2075 0.00064 phosphoserine phosphatase SerB K01079. | 0.668 |
| apt | KWZ72064.1 | HMPREF3198_02169 | HMPREF3198_02162 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | DNA-binding regulatory protein, YebC/PmpR family; KEGG: rdn:HMPREF0733_12022 5.2e-77 glucose-1-phosphate adenylyltransferase. | 0.516 |
| apt | ruvA | HMPREF3198_02169 | HMPREF3198_02164 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.541 |
| apt | ruvB | HMPREF3198_02169 | HMPREF3198_02165 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.541 |
| apt | ruvC | HMPREF3198_02169 | HMPREF3198_02163 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.526 |
| apt | secD | HMPREF3198_02169 | HMPREF3198_02167 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.849 |
| apt | secF | HMPREF3198_02169 | HMPREF3198_02168 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.827 |
| apt | yajC | HMPREF3198_02169 | HMPREF3198_02166 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Preprotein translocase, YajC subunit; KEGG: mel:Metbo_2075 0.00064 phosphoserine phosphatase SerB K01079. | 0.637 |
| rpsD | tig | HMPREF3198_02183 | HMPREF3198_01805 | Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.986 |
| rpsD | tsf | HMPREF3198_02183 | HMPREF3198_01259 | Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.963 |
| rpsD | yajC | HMPREF3198_02183 | HMPREF3198_02166 | Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | Preprotein translocase, YajC subunit; KEGG: mel:Metbo_2075 0.00064 phosphoserine phosphatase SerB K01079. | 0.596 |
| ruvA | KWZ72064.1 | HMPREF3198_02164 | HMPREF3198_02162 | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | DNA-binding regulatory protein, YebC/PmpR family; KEGG: rdn:HMPREF0733_12022 5.2e-77 glucose-1-phosphate adenylyltransferase. | 0.757 |
| ruvA | apt | HMPREF3198_02164 | HMPREF3198_02169 | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.541 |
