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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (517 aa)    
Predicted Functional Partners:
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
 0.999
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
 0.999
KWZ72091.1
KEGG: iva:Isova_1625 2.4e-47 shikimate dehydrogenase; K00014 shikimate dehydrogenase; Belongs to the shikimate dehydrogenase family.
 
 0.998
KWZ72095.1
Shikimate kinase; KEGG: tfu:Tfu_1091 1.1e-19 aroK; shikimate kinase K00891; Psort location: Cytoplasmic, score: 7.50.
 
 
0.988
aroD
3-dehydroquinate dehydratase, type I; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family.
 
 
 0.985
der
Ribosome biogenesis GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the cytidylate kinase family. Type 1 subfamily.
 
 
 0.972
KWZ72453.1
Chorismate mutase; KEGG: mcu:HMPREF0573_11431 1.8e-33 pheA; chorismate mutase K04092; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.959
KWZ74482.1
KEGG: cga:Celgi_0175 8.8e-82 prephenate dehydratase; K04518 prephenate dehydratase; Psort location: Cytoplasmic, score: 9.67.
 
 
 0.956
pabB
Aminodeoxychorismate synthase, component I; KEGG: scy:SCATT_14640 5.7e-110 para-aminobenzoate synthase; K13950 para-aminobenzoate synthetase; Psort location: Cytoplasmic, score: 9.95.
 
 
 0.954
KWZ72153.1
KEGG: mcu:HMPREF0573_11798 3.9e-159 aroH; 3-deoxy-7-phosphoheptulonate synthase K01626; Psort location: Cytoplasmic, score: 7.50; Belongs to the class-II DAHP synthase family.
    
 0.949
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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