| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KWZ72091.1 | KWZ72092.1 | HMPREF3198_02189 | HMPREF3198_02190 | KEGG: iva:Isova_1625 2.4e-47 shikimate dehydrogenase; K00014 shikimate dehydrogenase; Belongs to the shikimate dehydrogenase family. | Hypothetical protein; KEGG: ica:Intca_1591 4.4e-06 peptidase A24A prepilin type IV; K02654 leader peptidase (prepilin peptidase) / N-methyltransferase; Psort location: CytoplasmicMembrane, score: 10.00. | 0.415 |
| KWZ72091.1 | KWZ72095.1 | HMPREF3198_02189 | HMPREF3198_02193 | KEGG: iva:Isova_1625 2.4e-47 shikimate dehydrogenase; K00014 shikimate dehydrogenase; Belongs to the shikimate dehydrogenase family. | Shikimate kinase; KEGG: tfu:Tfu_1091 1.1e-19 aroK; shikimate kinase K00891; Psort location: Cytoplasmic, score: 7.50. | 0.741 |
| KWZ72091.1 | aroA | HMPREF3198_02189 | HMPREF3198_01382 | KEGG: iva:Isova_1625 2.4e-47 shikimate dehydrogenase; K00014 shikimate dehydrogenase; Belongs to the shikimate dehydrogenase family. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.982 |
| KWZ72091.1 | aroB | HMPREF3198_02189 | HMPREF3198_02192 | KEGG: iva:Isova_1625 2.4e-47 shikimate dehydrogenase; K00014 shikimate dehydrogenase; Belongs to the shikimate dehydrogenase family. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.987 |
| KWZ72091.1 | aroC | HMPREF3198_02189 | HMPREF3198_02191 | KEGG: iva:Isova_1625 2.4e-47 shikimate dehydrogenase; K00014 shikimate dehydrogenase; Belongs to the shikimate dehydrogenase family. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.947 |
| KWZ72091.1 | efp | HMPREF3198_02189 | HMPREF3198_02194 | KEGG: iva:Isova_1625 2.4e-47 shikimate dehydrogenase; K00014 shikimate dehydrogenase; Belongs to the shikimate dehydrogenase family. | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 0.441 |
| KWZ72091.1 | mltG | HMPREF3198_02189 | HMPREF3198_02188 | KEGG: iva:Isova_1625 2.4e-47 shikimate dehydrogenase; K00014 shikimate dehydrogenase; Belongs to the shikimate dehydrogenase family. | YceG family protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. | 0.909 |
| KWZ72091.1 | nusB | HMPREF3198_02189 | HMPREF3198_02195 | KEGG: iva:Isova_1625 2.4e-47 shikimate dehydrogenase; K00014 shikimate dehydrogenase; Belongs to the shikimate dehydrogenase family. | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.507 |
| KWZ72092.1 | KWZ72091.1 | HMPREF3198_02190 | HMPREF3198_02189 | Hypothetical protein; KEGG: ica:Intca_1591 4.4e-06 peptidase A24A prepilin type IV; K02654 leader peptidase (prepilin peptidase) / N-methyltransferase; Psort location: CytoplasmicMembrane, score: 10.00. | KEGG: iva:Isova_1625 2.4e-47 shikimate dehydrogenase; K00014 shikimate dehydrogenase; Belongs to the shikimate dehydrogenase family. | 0.415 |
| KWZ72092.1 | KWZ72095.1 | HMPREF3198_02190 | HMPREF3198_02193 | Hypothetical protein; KEGG: ica:Intca_1591 4.4e-06 peptidase A24A prepilin type IV; K02654 leader peptidase (prepilin peptidase) / N-methyltransferase; Psort location: CytoplasmicMembrane, score: 10.00. | Shikimate kinase; KEGG: tfu:Tfu_1091 1.1e-19 aroK; shikimate kinase K00891; Psort location: Cytoplasmic, score: 7.50. | 0.610 |
| KWZ72092.1 | aroB | HMPREF3198_02190 | HMPREF3198_02192 | Hypothetical protein; KEGG: ica:Intca_1591 4.4e-06 peptidase A24A prepilin type IV; K02654 leader peptidase (prepilin peptidase) / N-methyltransferase; Psort location: CytoplasmicMembrane, score: 10.00. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.610 |
| KWZ72092.1 | aroC | HMPREF3198_02190 | HMPREF3198_02191 | Hypothetical protein; KEGG: ica:Intca_1591 4.4e-06 peptidase A24A prepilin type IV; K02654 leader peptidase (prepilin peptidase) / N-methyltransferase; Psort location: CytoplasmicMembrane, score: 10.00. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.610 |
| KWZ72092.1 | efp | HMPREF3198_02190 | HMPREF3198_02194 | Hypothetical protein; KEGG: ica:Intca_1591 4.4e-06 peptidase A24A prepilin type IV; K02654 leader peptidase (prepilin peptidase) / N-methyltransferase; Psort location: CytoplasmicMembrane, score: 10.00. | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 0.461 |
| KWZ72092.1 | mltG | HMPREF3198_02190 | HMPREF3198_02188 | Hypothetical protein; KEGG: ica:Intca_1591 4.4e-06 peptidase A24A prepilin type IV; K02654 leader peptidase (prepilin peptidase) / N-methyltransferase; Psort location: CytoplasmicMembrane, score: 10.00. | YceG family protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. | 0.415 |
| KWZ72092.1 | nusB | HMPREF3198_02190 | HMPREF3198_02195 | Hypothetical protein; KEGG: ica:Intca_1591 4.4e-06 peptidase A24A prepilin type IV; K02654 leader peptidase (prepilin peptidase) / N-methyltransferase; Psort location: CytoplasmicMembrane, score: 10.00. | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.461 |
| KWZ72095.1 | KWZ72091.1 | HMPREF3198_02193 | HMPREF3198_02189 | Shikimate kinase; KEGG: tfu:Tfu_1091 1.1e-19 aroK; shikimate kinase K00891; Psort location: Cytoplasmic, score: 7.50. | KEGG: iva:Isova_1625 2.4e-47 shikimate dehydrogenase; K00014 shikimate dehydrogenase; Belongs to the shikimate dehydrogenase family. | 0.741 |
| KWZ72095.1 | KWZ72092.1 | HMPREF3198_02193 | HMPREF3198_02190 | Shikimate kinase; KEGG: tfu:Tfu_1091 1.1e-19 aroK; shikimate kinase K00891; Psort location: Cytoplasmic, score: 7.50. | Hypothetical protein; KEGG: ica:Intca_1591 4.4e-06 peptidase A24A prepilin type IV; K02654 leader peptidase (prepilin peptidase) / N-methyltransferase; Psort location: CytoplasmicMembrane, score: 10.00. | 0.610 |
| KWZ72095.1 | KWZ72637.1 | HMPREF3198_02193 | HMPREF3198_01996 | Shikimate kinase; KEGG: tfu:Tfu_1091 1.1e-19 aroK; shikimate kinase K00891; Psort location: Cytoplasmic, score: 7.50. | KEGG: bcv:Bcav_2151 3.3e-82 prephenate dehydrogenase; K04517 prephenate dehydrogenase; Psort location: Cytoplasmic, score: 7.50. | 0.579 |
| KWZ72095.1 | aroA | HMPREF3198_02193 | HMPREF3198_01382 | Shikimate kinase; KEGG: tfu:Tfu_1091 1.1e-19 aroK; shikimate kinase K00891; Psort location: Cytoplasmic, score: 7.50. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.683 |
| KWZ72095.1 | aroB | HMPREF3198_02193 | HMPREF3198_02192 | Shikimate kinase; KEGG: tfu:Tfu_1091 1.1e-19 aroK; shikimate kinase K00891; Psort location: Cytoplasmic, score: 7.50. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.957 |