STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
pyrRPyrimidine operon regulatory protein/uracil phosphoribosyltransferase PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. (182 aa)    
Predicted Functional Partners:
pyrB
KEGG: mcu:HMPREF0573_11715 2.1e-121 pyrB; aspartate carbamoyltransferase K00609; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
 0.999
pyrC
Putative dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
 
 
 0.987
carB
KEGG: bcv:Bcav_2038 0. carbamoyl-phosphate synthase large subunit; K01955 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family.
  
  
 0.969
pyrF
KEGG: iva:Isova_1604 2.0e-68 Orotidine 5'-phosphate decarboxylase K01591; Psort location: Cytoplasmic, score: 7.50; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
  
 0.943
carA
KEGG: cga:Celgi_1781 6.0e-138 carbamoyl-phosphate synthase, small subunit; K01956 carbamoyl-phosphate synthase small subunit; Psort location: Cytoplasmic, score: 7.50; Belongs to the CarA family.
  
  
 0.927
pyrH
UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
     
 0.918
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
     
 0.916
rihB
Putative cytidine/uridine-specific hydrolase; KEGG: aau:AAur_3646 2.1e-119 inosine-uridine preferring nucleoside hydrolase (IunH); K01239 purine nucleosidase; Psort location: Cytoplasmic, score: 7.50.
     
  0.900
KWZ75210.1
HAD hydrolase family; KEGG: mcu:HMPREF0573_10527 7.0e-89 pdxP; putative pyridoxal phosphatase K02566; Belongs to the HAD-like hydrolase superfamily.
     
  0.900
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
  
 0.822
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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