STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrCPutative dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (433 aa)    
Predicted Functional Partners:
pyrB
KEGG: mcu:HMPREF0573_11715 2.1e-121 pyrB; aspartate carbamoyltransferase K00609; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 0.999
carA
KEGG: cga:Celgi_1781 6.0e-138 carbamoyl-phosphate synthase, small subunit; K01956 carbamoyl-phosphate synthase small subunit; Psort location: Cytoplasmic, score: 7.50; Belongs to the CarA family.
  
 0.998
carB
KEGG: bcv:Bcav_2038 0. carbamoyl-phosphate synthase large subunit; K01955 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family.
 
 0.998
pyrR
Pyrimidine operon regulatory protein/uracil phosphoribosyltransferase PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
 
 
 0.995
KWZ72166.1
Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
 0.994
pyrF
KEGG: iva:Isova_1604 2.0e-68 Orotidine 5'-phosphate decarboxylase K01591; Psort location: Cytoplasmic, score: 7.50; Belongs to the OMP decarboxylase family. Type 2 subfamily.
 
  
 0.971
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
 
 0.954
KWZ72123.1
Xanthine permease; KEGG: apb:SAR116_1372 8.1e-56 xanthine/uracil permease K03458; Psort location: CytoplasmicMembrane, score: 10.00.
  
 
 0.907
KWZ75626.1
Putative permease; KEGG: hiq:CGSHiGG_01870 2.3e-49 upp; uracil phosphoribosyltransferase K02824; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.734
KWZ72091.1
KEGG: iva:Isova_1625 2.4e-47 shikimate dehydrogenase; K00014 shikimate dehydrogenase; Belongs to the shikimate dehydrogenase family.
     
 0.691
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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