| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KWZ72122.1 | KWZ72123.1 | HMPREF3198_02220 | HMPREF3198_02221 | Transporter, major facilitator family protein; KEGG: sna:Snas_2521 1.3e-16 aspartyl-tRNA synthetase; K01876 aspartyl-tRNA synthetase; Psort location: CytoplasmicMembrane, score: 10.00. | Xanthine permease; KEGG: apb:SAR116_1372 8.1e-56 xanthine/uracil permease K03458; Psort location: CytoplasmicMembrane, score: 10.00. | 0.556 |
| KWZ72123.1 | KWZ72122.1 | HMPREF3198_02221 | HMPREF3198_02220 | Xanthine permease; KEGG: apb:SAR116_1372 8.1e-56 xanthine/uracil permease K03458; Psort location: CytoplasmicMembrane, score: 10.00. | Transporter, major facilitator family protein; KEGG: sna:Snas_2521 1.3e-16 aspartyl-tRNA synthetase; K01876 aspartyl-tRNA synthetase; Psort location: CytoplasmicMembrane, score: 10.00. | 0.556 |
| KWZ72123.1 | KWZ72163.1 | HMPREF3198_02221 | HMPREF3198_02261 | Xanthine permease; KEGG: apb:SAR116_1372 8.1e-56 xanthine/uracil permease K03458; Psort location: CytoplasmicMembrane, score: 10.00. | Hypothetical protein; KEGG: srt:Srot_2267 1.7e-13 glycerate kinase K00865; Psort location: CytoplasmicMembrane, score: 8.16. | 0.555 |
| KWZ72123.1 | KWZ72166.1 | HMPREF3198_02221 | HMPREF3198_02264 | Xanthine permease; KEGG: apb:SAR116_1372 8.1e-56 xanthine/uracil permease K03458; Psort location: CytoplasmicMembrane, score: 10.00. | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.685 |
| KWZ72123.1 | KWZ75271.1 | HMPREF3198_02221 | HMPREF3198_00161 | Xanthine permease; KEGG: apb:SAR116_1372 8.1e-56 xanthine/uracil permease K03458; Psort location: CytoplasmicMembrane, score: 10.00. | Putative permease; KEGG: bcz:BCZK0244 6.8e-75 guanine-hypoxanthine permease; xanthine/uracil permease family protein K06901; Psort location: CytoplasmicMembrane, score: 10.00. | 0.534 |
| KWZ72123.1 | carB | HMPREF3198_02221 | HMPREF3198_02200 | Xanthine permease; KEGG: apb:SAR116_1372 8.1e-56 xanthine/uracil permease K03458; Psort location: CytoplasmicMembrane, score: 10.00. | KEGG: bcv:Bcav_2038 0. carbamoyl-phosphate synthase large subunit; K01955 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | 0.706 |
| KWZ72123.1 | pyrB | HMPREF3198_02221 | HMPREF3198_02197 | Xanthine permease; KEGG: apb:SAR116_1372 8.1e-56 xanthine/uracil permease K03458; Psort location: CytoplasmicMembrane, score: 10.00. | KEGG: mcu:HMPREF0573_11715 2.1e-121 pyrB; aspartate carbamoyltransferase K00609; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.785 |
| KWZ72123.1 | pyrC | HMPREF3198_02221 | HMPREF3198_02198 | Xanthine permease; KEGG: apb:SAR116_1372 8.1e-56 xanthine/uracil permease K03458; Psort location: CytoplasmicMembrane, score: 10.00. | Putative dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.746 |
| KWZ72123.1 | pyrE | HMPREF3198_02221 | HMPREF3198_00193 | Xanthine permease; KEGG: apb:SAR116_1372 8.1e-56 xanthine/uracil permease K03458; Psort location: CytoplasmicMembrane, score: 10.00. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.699 |
| KWZ72123.1 | pyrF | HMPREF3198_02221 | HMPREF3198_02201 | Xanthine permease; KEGG: apb:SAR116_1372 8.1e-56 xanthine/uracil permease K03458; Psort location: CytoplasmicMembrane, score: 10.00. | KEGG: iva:Isova_1604 2.0e-68 Orotidine 5'-phosphate decarboxylase K01591; Psort location: Cytoplasmic, score: 7.50; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.719 |
| KWZ72123.1 | pyrR | HMPREF3198_02221 | HMPREF3198_02196 | Xanthine permease; KEGG: apb:SAR116_1372 8.1e-56 xanthine/uracil permease K03458; Psort location: CytoplasmicMembrane, score: 10.00. | Pyrimidine operon regulatory protein/uracil phosphoribosyltransferase PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.747 |
| KWZ72163.1 | KWZ72123.1 | HMPREF3198_02261 | HMPREF3198_02221 | Hypothetical protein; KEGG: srt:Srot_2267 1.7e-13 glycerate kinase K00865; Psort location: CytoplasmicMembrane, score: 8.16. | Xanthine permease; KEGG: apb:SAR116_1372 8.1e-56 xanthine/uracil permease K03458; Psort location: CytoplasmicMembrane, score: 10.00. | 0.555 |
| KWZ72166.1 | KWZ72123.1 | HMPREF3198_02264 | HMPREF3198_02221 | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Xanthine permease; KEGG: apb:SAR116_1372 8.1e-56 xanthine/uracil permease K03458; Psort location: CytoplasmicMembrane, score: 10.00. | 0.685 |
| KWZ72166.1 | carB | HMPREF3198_02264 | HMPREF3198_02200 | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | KEGG: bcv:Bcav_2038 0. carbamoyl-phosphate synthase large subunit; K01955 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | 0.973 |
| KWZ72166.1 | pyrB | HMPREF3198_02264 | HMPREF3198_02197 | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | KEGG: mcu:HMPREF0573_11715 2.1e-121 pyrB; aspartate carbamoyltransferase K00609; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.967 |
| KWZ72166.1 | pyrC | HMPREF3198_02264 | HMPREF3198_02198 | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Putative dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.956 |
| KWZ72166.1 | pyrE | HMPREF3198_02264 | HMPREF3198_00193 | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.961 |
| KWZ72166.1 | pyrF | HMPREF3198_02264 | HMPREF3198_02201 | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | KEGG: iva:Isova_1604 2.0e-68 Orotidine 5'-phosphate decarboxylase K01591; Psort location: Cytoplasmic, score: 7.50; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.957 |
| KWZ72166.1 | pyrR | HMPREF3198_02264 | HMPREF3198_02196 | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Pyrimidine operon regulatory protein/uracil phosphoribosyltransferase PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.754 |
| KWZ75271.1 | KWZ72123.1 | HMPREF3198_00161 | HMPREF3198_02221 | Putative permease; KEGG: bcz:BCZK0244 6.8e-75 guanine-hypoxanthine permease; xanthine/uracil permease family protein K06901; Psort location: CytoplasmicMembrane, score: 10.00. | Xanthine permease; KEGG: apb:SAR116_1372 8.1e-56 xanthine/uracil permease K03458; Psort location: CytoplasmicMembrane, score: 10.00. | 0.534 |