STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KWZ72157.1GIY-YIG catalytic domain protein; KEGG: bcv:Bcav_1900 1.8e-106 hypothetical protein; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 9.67. (582 aa)    
Predicted Functional Partners:
KWZ72524.1
Hypothetical protein; KEGG: bcv:Bcav_2435 3.8e-136 helicase c2; K03722 ATP-dependent DNA helicase DinG; Psort location: Cytoplasmic, score: 7.50.
   
 0.962
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
 
 
 0.957
KWZ74693.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.951
holA
KEGG: bcv:Bcav_1739 1.2e-75 DNA polymerase III subunit delta; K02340 DNA polymerase III subunit delta; Psort location: Cellwall, score: 8.19.
    
 0.951
KWZ75212.1
KEGG: iva:Isova_2736 4.7e-170 DNA polymerase III subunits gamma and tau; K02343 DNA polymerase III subunit gamma/tau; Psort location: Cytoplasmic, score: 9.97.
  
 0.946
KWZ75030.1
KEGG: iva:Isova_0427 6.0e-115 DNA polymerase III, delta prime subunit; K02341 DNA polymerase III subunit delta'; Psort location: Cytoplasmic, score: 9.97.
  
 0.946
KWZ73128.1
Hypothetical protein; KEGG: mcu:HMPREF0573_11531 1.4e-28 dnaQ; DNA polymerase III subunit epsilon K02342; Psort location: Cytoplasmic, score: 7.50.
    
 0.946
KWZ72552.1
KEGG: bfa:Bfae_10990 0. dnaE; DNA polymerase III subunit alpha; K02337 DNA polymerase III subunit alpha; Psort location: Cytoplasmic, score: 9.97.
    
 0.945
ligA
DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
  
 
 0.924
KWZ74942.1
HRDC domain protein; KEGG: xce:Xcel_0786 8.9e-192 UvrD/REP helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.901
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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