Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AOG29120.1DNA protecting protein DprA; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)    
Predicted Functional Partners:
AOG29119.1
Mg chelatase-like protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.968
AOG29118.1
YraN family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0102 family.
 
  
 0.937
AOG29223.1
Competence protein ComE; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.831
AOG29149.1
Amidophosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.643
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
  
    0.607
AOG29116.1
Signal peptidase I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family.
 
     0.596
AOG29117.1
Protein often found in actinomycetes clustered with signal peptidase and/or RNaseHII; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.594
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
   
 0.571
AOG29148.1
Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.503
AOG27284.1
DNA helicase II; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.479
Your Current Organism:
Cutibacterium avidum
NCBI taxonomy Id: 33010
Other names: ATCC 25577, Bacteroides avidus, C. avidum, CCUG 36754, CIP 103261, Corynebacterium avidum, DSM 4901, IFO 15671, Mycobacterium avidum, NBRC 15671, NCTC 11864, Propionibacterium avidum, Propionicibacterium avidum
Server load: low (20%) [HD]