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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pchF4-cresol dehydrogenase (hydroxylating), flavoprotein subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (514 aa)    
Predicted Functional Partners:
nuoCD
NADH-quinone oxidoreductase, subunits C and D; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
   
 
 0.829
xylB
Aryl-alcohol dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.804
pchC
4-cresol dehydrogenase (hydroxylating), cytochrome c subunit; Function of homologous gene experimentally demonstrated in an other organism; carrier.
   
   0.752
NIDE0021
Homologs of previously reported genes of unknown function.
       0.718
atpD
ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.
    
 0.653
ubiA
4-hydroxybenzoate octaprenyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the UbiA prenyltransferase family.
    
 0.627
NIDE3581
Putative Prenyltransferase, UbiA family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the UbiA prenyltransferase family.
    
 0.627
atpE
ATP synthase F0, subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
   
 
  0.552
NIDE3861
Homologs of previously reported genes of unknown function.
  
    0.531
NIDE4364
Conserved protein of unknown function, contains TPR repeats; Homologs of previously reported genes of unknown function; 15451670, 1882418, 7667876, 9482716.
  
     0.527
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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