Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pchF4-cresol dehydrogenase (hydroxylating), flavoprotein subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (514 aa)    
Predicted Functional Partners:
xylB
Aryl-alcohol dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.800
pchC
4-cresol dehydrogenase (hydroxylating), cytochrome c subunit; Function of homologous gene experimentally demonstrated in an other organism; carrier.
   
   0.747
NIDE0021
Homologs of previously reported genes of unknown function.
       0.718
nuoCD
NADH-quinone oxidoreductase, subunits C and D; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
   
   0.611
NIDE3861
Homologs of previously reported genes of unknown function.
  
    0.530
NIDE4364
Conserved protein of unknown function, contains TPR repeats; Homologs of previously reported genes of unknown function; 15451670, 1882418, 7667876, 9482716.
  
     0.527
NIDE3330
Conserved protein of unknown function, SDR family; Homologs of previously reported genes of unknown function; 7742302.
   
 
 0.515
NIDE0024
Exported protein of unknown function; No homology to any previously reported sequences.
       0.502
atpH
Putative ATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
  
 
  0.497
NIDE0058
Homologs of previously reported genes of unknown function.
  
     0.494
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.