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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE0047Nitroreductase; Function of strongly homologous gene; enzyme. (201 aa)    
Predicted Functional Partners:
leuA
2-Isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
     
 0.701
NIDE4110
2-isopropylmalate/homocitrate synthase-family transferase; Function of strongly homologous gene; enzyme; Belongs to the alpha-IPM synthase/homocitrate synthase family.
     
 0.701
glnB
Nitrogen regulatory protein PII; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the P(II) protein family.
   
  
 0.700
glnB-2
Nitrogen regulatory protein P-II; Function of strongly homologous gene; regulator.
   
  
 0.700
glnB-3
Nitrogen regulatory protein P-II; Function of strongly homologous gene; regulator.
   
  
 0.700
rpoE
RNA polymerase sigma 24 (sigma E) factor; Function of homologous gene experimentally demonstrated in an other organism; factor; Belongs to the sigma-70 factor family. ECF subfamily.
      
 0.699
NIDE0045
Putative Phosphoglycolate phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
    0.689
maa
Maltose O-acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.686
bcp
Peroxiredoxin; Function of strongly homologous gene; enzyme.
 
 
    0.671
pdxJ
Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
     
 0.619
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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